Development of gatekeeping strategies in confirmatory clinical trials

DOI10.1002/BIMJ.201100036zbMATH Open1238.62127OpenAlexW1975798555WikidataQ48030809 ScholiaQ48030809MaRDI QIDQ2889660FDOQ2889660

Authors: Alex Dmitrienko, Brian A. Millen, Thomas Brechenmacher, Gautier Paux 

Publication date: 8 June 2012

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.201100036

Recommendations

• General theory of mixture procedures for gatekeeping
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zbMATH Keywords

powermultiple testsfamilywise error rate

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Paired and multiple comparisons; multiple testing (62J15)

Cites Work

• Testing for efficacy in primary and secondary endpoints by partitioning decision paths
• On closed testing procedures with special reference to ordered analysis of variance
• The Simes Method for Multiple Hypothesis Testing With Positively Dependent Test Statistics
• Optimally weighted, fixed sequence and gatekeeper multiple testing procedures
• Some probability inequalities for ordered MTP\(_2\) random variables: a proof of the Simes conjecture

Cited In (2)

• Panel forum on multiple comparison procedures: A commentary from a complex trial design and analysis plan
• General theory of mixture procedures for gatekeeping

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