A dynamic multi-compartmental model of DNA methylation with demonstrable predictive value in hematological malignancies

DOI10.1016/J.JTBI.2012.06.018zbMATH Open1337.92063OpenAlexW2040801747WikidataQ51351456 ScholiaQ51351456MaRDI QIDQ292736FDOQ292736

Authors: Andrew P. McGovern, Benjamin E. Powell, Timothy J. T. Chevassut 

Publication date: 9 June 2016

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2012.06.018

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zbMATH Keywords

CpG islandDNA methyltransferase (Dnmt)hydroxymethylcytosinemethylcytosineTet protein

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40)

Cites Work

• Dynamics, stability and inheritance of somatic DNA methylation imprints

Cited In (4)

• A mathematical model for inheritance of DNA methylation patterns in somatic cells
• Modeling dependence in methylation patterns with application to ovarian carcinomas
• Data-driven selection and parameter estimation for DNA methylation mathematical models
• Mathematical models of DNA methylation dynamics: implications for health and ageing

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