A dynamic multi-compartmental model of DNA methylation with demonstrable predictive value in hematological malignancies

DOI10.1016/J.JTBI.2012.06.018MaRDI QIDQ292736zbMATH OpenOpenAlexWikidataFDO

Authors Andrew P. McGovern, Benjamin E. Powell, Timothy J. T. Chevassut

Publication date 9 June 2016

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2012.06.018

zbMATH Keywords

CpG islandDNA methyltransferase (Dnmt)hydroxymethylcytosinemethylcytosineTet protein

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40)

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Cites work

• Dynamics, stability and inheritance of somatic DNA methylation imprints

Cited in

(9)

• A mathematical model for inheritance of DNA methylation patterns in somatic cells
• Predicting methylation from sequence and gene expression using deep learning with attention
• A stochastic model for the formation of spatial methylation patterns
• Dynamics, stability and inheritance of somatic DNA methylation imprints
• Modeling dependence in methylation patterns with application to ovarian carcinomas
• A stochastic automata network description for spatial DNA-methylation models
• Data-driven selection and parameter estimation for DNA methylation mathematical models
• Cell type-dependent, infection-induced, aberrant DNA methylation in gastric cancer
• Mathematical models of DNA methylation dynamics: implications for health and ageing

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