A Wolbachia infection model with free boundary
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Publication:3304367
Abstract: Scientists have been seeking ways to use Wolbachia to eliminate the mosquitoes that spread human diseases. Could Wolbachia be the determining factor in controlling the mosquito-borne infectious diseases? To answer this question mathematically, we develop a reaction-diffusion model with free boundary in a one-dimensional environment. We divide the female mosquito population into two groups: one is the uninfected mosquito population that grows in the whole region while the other is the mosquito population infected with Wolbachia that occupies a finite small region and invades the environment with a spreading front governed by a free boundary satisfying the well-known one-phase Stefan condition. For the resulting free boundary problem, we establish criteria under which spreading and vanishing occur. Our results provide useful insights on designing a feasible mosquito releasing strategy to invade the whole mosquito population with Wolbachia infection and thus eventually eradicate the mosquito-borne diseases.
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