Optimization of spatial control strategies for population replacement, application toWolbachia
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Publication:3383282
Abstract: In this article, we are interested in the analysis and simulation of solutions to an optimal control problem motivated by population dynamics issues. In order to control the spread of mosquito-borne arboviruses, the population replacement technique consists in releasing into the environment mosquitoes infected with the Wolbachia bacterium, which greatly reduces the transmission of the virus to the humans. Spatial releases are then sought in such a way that the infected mosquito population invades the uninfected mosquito population. Assuming very high mosquito fecundity rates, we first introduce an asymptotic model on the proportion of infected mosquitoes and then an optimal control problem to determine the best spatial strategy to achieve these releases. We then analyze this problem, including the optimality of natural candidates and carry out first numerical simulations in one dimension of space to illustrate the relevance of our approach.
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Cited in
(7)- Optimal release of mosquitoes to control dengue transmission
- Minimal cost-time strategies for mosquito population replacement
- Optimal releases for population replacement strategies: application to Wolbachia
- Optimal control strategies for the sterile mosquitoes technique
- Vector-borne disease outbreak control via instant releases
- Mosquito population control strategies for fighting against arboviruses
- Optimisation of the total population size with respect to the initial condition for semilinear parabolic equations: two-scale expansions and symmetrisations
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