Haplotypes: the joint distribution of alleles at linked loci

DOI10.1239/JAP/1053003559MaRDI QIDQ4435690zbMATH OpenOpenAlexFDO

Authors Paul Fearnhead

Publication date 17 November 2003

Published in Journal of Applied Probability (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1239/jap/1053003559

zbMATH Keywords

selectionmutationrecombinationstationary distributionancestral selection graphmost recent common ancestorancestral influence graph

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Problems related to evolution (92D15) Markov chains (discrete-time Markov processes on discrete state spaces) (60J10) Applications of branching processes (60J85) Stationary stochastic processes (60G10)

Recommendations

• The stationary distribution of allele frequencies when selection acts at unlinked loci
• Allelic frequencies given the sample's common ancestral type
• Conditional ancestral times and related properties of an extant mutant at a locus A given the number of segregating sites observed at a linked locus B
• Which locus has the oldest allele?
• Probability distribution of haplotype frequencies under the two-locus Wright-Fisher model by diffusion approximation

Cites work

• scientific article; zbMATH DE number 1094276 (Why is no real title available?)
• Ancestral inference in population genetics
• Ancestral processes with selection
• Genealogical processes for Fleming-Viot models with selection and recombination
• Markov Chains
• Simulation of selected genealogies.

Cited in

(4)

• A coalescent dual process for a Wright-Fisher diffusion with recombination and its application to haplotype partitioning
• Consistency of estimators of the population-scaled recombination rate
• Padé approximants and exact two-locus sampling distributions
• Ancestral processes for non-neutral models of complex diseases

This page was built for publication: Haplotypes: the joint distribution of alleles at linked loci

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q4435690)