Stochastic models for evolving cellular populations of mitochondria: disease, development, and ageing

DOI10.1007/978-3-319-62627-7_13zbMATH Open1401.92066OpenAlexW2761239962MaRDI QIDQ4555239FDOQ4555239

Authors Hanne Hoitzing, Iain G. Johnston, Nick S. Jones 

Publication date 19 November 2018

Published in Stochastic Processes, Multiscale Modeling, and Numerical Methods for Computational Cellular Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/978-3-319-62627-7_13

zbMATH Keywords

mitochondriamtDNAheteroplasmymitochondrial dysfunctions

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Cell biology (92C37)

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Cites work

• A model of the nuclear control of mitochondrial DNA replication
• Bayesian emulation and calibration of a stochastic computer model of mitochondrial DNA deletions in substantia nigra neurons
• Closed-form stochastic solutions for non-equilibrium dynamics and inheritance of cellular components over many cell divisions
• Efficient parametric inference for stochastic biological systems with measured variability
• Mitochondrial mutations and ageing: can mitochondrial deletion mutants accumulate via a size based replication advantage?
• SOLUTION OF A PROCESS OF RANDOM GENETIC DRIFT WITH A CONTINUOUS MODEL
• Stochastic methods. A handbook for the natural and social sciences
• Stochastic processes in physics and chemistry.

Cited in

(5)

• A model of the nuclear control of mitochondrial DNA replication
• scientific article; zbMATH DE number 1405848 (Why is no real title available?)
• Stochastic simulations of normal aging and Werner's syndrome
• Closed-form stochastic solutions for non-equilibrium dynamics and inheritance of cellular components over many cell divisions
• Stability in generic mitochondrial models

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