The Moran model with selection: fixation probabilities, ancestral lines, and an alternative particle representation

DOI10.1016/J.TPB.2013.09.009zbMATH Open1303.92072arXiv1306.2772OpenAlexW2963537990WikidataQ86046016 ScholiaQ86046016MaRDI QIDQ487316FDOQ487316

Authors: Sandra Kluth, Ellen Baake 

Publication date: 20 January 2015

Published in: Theoretical Population Biology (Search for Journal in Brave)

Abstract: We reconsider the Moran model in continuous time with population size $N$, two allelic types, and selection. We introduce a new particle representation, which we call the labelled Moran model, and which has the same distribution of type frequencies as the original Moran model, provided the initial values are chosen appropriately. In the new model, individuals are labelled $1,2,dots,N$; neutral resampling events may take place between arbitrary labels, whereas selective events only occur in the direction of increasing labels. With the help of elementary methods only, we not only recover fixation probabilities, but also obtain detailed insight into the number and nature of the selective events that play a role in the fixation process forward in time.

Full work available at URL: https://arxiv.org/abs/1306.2772

Recommendations

• The common ancestor process revisited
• Ancestral processes with selection: branching and Moran models
• Lines of descent in a Moran model with frequency-dependent selection and mutation
• Looking backwards in time in the Moran model in population genetics
• The transient behaviour of the Moran model in population genetics

zbMATH Keywords

fixation probabilityancestral linedefining eventlabelled Moran modelMoran model with selection

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Problems related to evolution (92D15)

Cites Work

• Mathematical population genetics. I: Theoretical introduction.
• Title not available (Why is that?)
• Probability Models for DNA Sequence Evolution
• Some mathematical models from population genetics. École d'Été de Probabilités de Saint-Flour XXXIX-2009
• Particle representations for measure-valued population models
• Ancestral processes with selection
• Genealogical processes for Fleming-Viot models with selection and recombination
• The common ancestor process for a Wright-Fisher diffusion
• The common ancestor process revisited
• A countable representation of the Fleming-Viot measure-valued diffusion
• The common ancestor at a nonneutral locus
• A look-down model with selection
• Duality, ancestral and diffusion processes in models with selection
• The ancestral selection graph under strong directional selection

Cited In (7)

• The common ancestor process revisited
• The evolving Moran genealogy
• Developments in coalescent theory from single loci to chromosomes
• Haldane's formula in Cannings models: the case of moderately weak selection
• Common ancestor type distribution: a Moran model and its deterministic limit
• A nearly-neutral biallelic Moran model with biased mutation and linear and quadratic selection
• The Wright-Fisher model with efficiency

This page was built for publication: The Moran model with selection: fixation probabilities, ancestral lines, and an alternative particle representation

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q487316)