The Moran model with selection: fixation probabilities, ancestral lines, and an alternative particle representation

DOI10.1016/J.TPB.2013.09.009MaRDI QIDQ487316zbMATH OpenOpenAlexWikidataFDO

Authors Sandra Kluth, Ellen Baake

Publication date 20 January 2015

Published in Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1306.2772

zbMATH Keywords

fixation probabilityancestral linedefining eventlabelled Moran modelMoran model with selection

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Problems related to evolution (92D15)

Abstract: We reconsider the Moran model in continuous time with population size $N$, two allelic types, and selection. We introduce a new particle representation, which we call the labelled Moran model, and which has the same distribution of type frequencies as the original Moran model, provided the initial values are chosen appropriately. In the new model, individuals are labelled $1,2,dots,N$; neutral resampling events may take place between arbitrary labels, whereas selective events only occur in the direction of increasing labels. With the help of elementary methods only, we not only recover fixation probabilities, but also obtain detailed insight into the number and nature of the selective events that play a role in the fixation process forward in time.

Recommendations

• The common ancestor process revisited
• Ancestral processes with selection: branching and Moran models
• Lines of descent in a Moran model with frequency-dependent selection and mutation
• Looking backwards in time in the Moran model in population genetics
• The transient behaviour of the Moran model in population genetics

Cites work

• scientific article; zbMATH DE number 3736679 (Why is no real title available?)
• A countable representation of the Fleming-Viot measure-valued diffusion
• A look-down model with selection
• Ancestral processes with selection
• Duality, ancestral and diffusion processes in models with selection
• Genealogical processes for Fleming-Viot models with selection and recombination
• Mathematical population genetics. I: Theoretical introduction.
• Particle representations for measure-valued population models
• Probability Models for DNA Sequence Evolution
• Some mathematical models from population genetics. École d'Été de Probabilités de Saint-Flour XXXIX-2009
• The ancestral selection graph under strong directional selection
• The common ancestor at a nonneutral locus
• The common ancestor process for a Wright-Fisher diffusion
• The common ancestor process revisited

Cited in

(7)

• The common ancestor process revisited
• The evolving Moran genealogy
• Developments in coalescent theory from single loci to chromosomes
• Haldane's formula in Cannings models: the case of moderately weak selection
• Common ancestor type distribution: a Moran model and its deterministic limit
• A nearly-neutral biallelic Moran model with biased mutation and linear and quadratic selection
• The Wright-Fisher model with efficiency

This page was built for publication: The Moran model with selection: fixation probabilities, ancestral lines, and an alternative particle representation

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q487316)