Identifying CpG islands: sliding window and hidden Markov model approaches

DOI10.1016/B978-0-12-415780-4.00009-0MaRDI QIDQ4981699zbMATH OpenOpenAlexFDO

Authors R. Robeva, Aaron Garrett, James R. Kirkwood, R. Davies

Publication date 24 June 2014

Published in Mathematical Concepts and Methods in Modern Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/b978-0-12-415780-4.00009-0

zbMATH Keywords

\(\mathrm{CpG}\) islandsBaum-Welch algorithmCpG island identificationDNA methylationDNA sequenceforward-backward algorithmhidden Markov modelposterior decodingsliding window algorithmtraining algorithmtumor suppressor promotersViterbi algorithmViterbi decoding

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Biochemistry, molecular biology (92C40) Protein sequences, DNA sequences (92D20)

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• scientific article; zbMATH DE number 1489817

Cited in

(2)

• Determining coding CpG islands by identifying regions significant for pattern statistics on Markov chains
• Redefining CpG islands using hidden Markov models

Describes a project that uses

Uses Software

• CpG Educate

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