A level-set approach for a multi-scale cancer invasion model
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Publication:5040326
DOI10.5206/MASE/11087zbMATH Open1498.92055arXiv1805.07485OpenAlexW3158513904WikidataQ111489579 ScholiaQ111489579MaRDI QIDQ5040326FDOQ5040326
Authors: T. Carraro, Sven E. Wetterauer, Ana Victoria Ponce Bobadilla, Dumitru Trucu 
Publication date: 11 October 2022
Published in: Mathematics in Applied Sciences and Engineering (Search for Journal in Brave)
Abstract: Central to the quest for a deeper understanding of the cancer growth and spread process, the naturally multiscale character of cancer invasion demands appropriate multiscale modelling and analysis approach. The cross-talk between the tissue scale (macro-scale) cancer cell population dynamics and the cell-scale (micro-scale) proteolytic molecular processes along the tumour boundary plays a particularly important role within the invasion processes, leading to dramatic changes in tumour morphology and influencing the overall pattern of cancer spread. Building on the multiscale moving boundary framework proposed in Trucu et al. (Multiscale Model. Simul 11(1): 309-335), in this work we propose a new formulation of this process involving a novel derivation of the macro-scale boundary movement law based on micro-dynamics, involving a transport equation combined with the level-set method. This is explored numerically in a novel finite element macro-micro framework based on cut-cells.
Full work available at URL: https://arxiv.org/abs/1805.07485
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PDEs in connection with biology, chemistry and other natural sciences (35Q92) Finite element, Rayleigh-Ritz and Galerkin methods for initial value and initial-boundary value problems involving PDEs (65M60) Pathology, pathophysiology (92C32)
Cites Work
- Algorithm 832
- Fronts propagating with curvature-dependent speed: Algorithms based on Hamilton-Jacobi formulations
- MATHEMATICAL MODELLING OF CANCER INVASION OF TISSUE: THE ROLE AND EFFECT OF NONLOCAL INTERACTIONS
- Convergence of a cancer invasion model to a logistic chemotaxis model
- Boundedness in the Higher-Dimensional Parabolic-Parabolic Chemotaxis System with Logistic Source
- How accurate is the streamline diffusion finite element method?
- MATHEMATICAL MODELLING OF CANCER CELL INVASION OF TISSUE: THE ROLE OF THE UROKINASE PLASMINOGEN ACTIVATION SYSTEM
- Mathematical modeling of cancer cell invasion of tissue: biological insight from mathematical analysis and computational simulation
- Multiscale modelling and nonlinear simulation of vascular tumour growth
- Nonlinear simulation of tumor necrosis, neo-vascularization and tissue invasion via an adaptive finite-element/level-set method
- Mathematical Modelling of Tumour Invasion and Metastasis
- Principles of multiscale modeling
- A positivity-preserving finite element method for chemotaxis problems in 3D
- Mathematical modelling of cancer cell invasion of tissue: local and non-local models and the effect of adhesion
- Multiphase modelling of tumour growth and extracellular matrix interaction: mathematical tools and applications
- Mathematical modelling of cancer invasion: implications of cell adhesion variability for tumour infiltrative growth patterns
- A new ghost cell/level set method for moving boundary problems: application to tumor growth
- The heterogeneous multiscale method
- Modelling solid tumour growth using the theory of mixtures
- Ghost penalty
- A simplified mathematical model of tumor growth
- Nonlinear simulation of the effect of microenvironment on tumor growth
- Directionality of macrophages movement in tumour invasion: a multiscale moving-boundary approach
- Mathematical modelling of cancer invasion: the importance of cell -- cell adhesion and cell -- matrix adhesion
- A hybrid mathematical model of solid tumour invasion: the importance of cell adhesion
- The heterogeneous multiscale methods
- Mathematical modelling of the loss of tissue compression responsiveness and its role in solid tumour development
- The fast construction of extension velocities in level set methods
- Modelling the role of cell-cell adhesion in the growth and development of carcinomas
- Three-dimensional multispecies nonlinear tumor growth. II: Tumor invasion and angiogenesis
- Three-dimensional multispecies nonlinear tumor growth. I: Model and numerical method
- A continuum approach to modelling cell-cell adhesion
- An improved geometry-aware curvature discretization for level set methods: Application to tumor growth
- Another look at velocity extensions in the level set method
- Multiphase modeling of tumor growth with matrix remodeling and fibrosis
- Evolving interfaces via gradients of geometry-dependent interior Poisson problems: application to tumor growth
- Multiscale modelling of cancer response to oncolytic viral therapy
- Multiscale modelling of fibres dynamics and cell adhesion within moving boundary cancer invasion
- A multiscale mathematical model of tumour invasive growth
- A multiscale moving boundary model arising in cancer invasion
- An analysis of a mathematical model of trophoblast invasion
- An adaptive multigrid algorithm for simulating solid tumor growth using mixture models
- On the design of algebraic flux correction schemes for quadratic finite elements
- Title not available (Why is that?)
- Efficient Approximation of Flow Problems With Multiple Scales in Time
- Multiscale computational modelling and analysis of cancer invasion
- The deal.II library, version 8.5
- Model of vascular desmoplastic multispecies tumor growth
- Multiscale moving boundary modelling of cancer interactions with a fusogenic oncolytic virus: the impact of syncytia dynamics
- Cell-scale degradation of peritumoural extracellular matrix fibre network and its role within tissue-scale cancer invasion
- Multiscale dynamics of a heterotypic cancer cell population within a fibrous extracellular matrix
- Non-local multiscale approaches for tumour-oncolytic viruses interactions
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