Mathematical model for transport of DNA plasmids from the external medium up to the nucleus by electroporation

DOI10.1016/J.MBS.2016.11.015MaRDI QIDQ512656zbMATH OpenOpenAlexWikidataFDO

Authors M. G. Notarangelo, Roberto Natalini, M. Leguèbe, Monika Twarogowska, Clair Poignard

Publication date 27 February 2017

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://hal.inria.fr/hal-01412380/file/Revision1.pdf

zbMATH Keywords

microtubulesintracellular transportfinite difference method in irregular domainsplasmids transport

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40)

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Cites work

• A parallel second order Cartesian method for elliptic interface problems
• A second-order Cartesian method for the simulation of electropermeabilization cell models
• A spatial model of cellular molecular trafficking including active transport along microtubules
• A spatial physiological model for p53 intracellular dynamics
• About the transmembrane voltage potential of a biological cell in time-harmonic regime.
• Conducting and permeable states of cell membrane submitted to high voltage pulses: mathematical and numerical studies validated by the experiments
• Influence of the nuclear membrane, active transport, and cell shape on the Hes1 and p53-Mdm2 pathways: insights from spatio-temporal modelling
• Modeling of pattern regulation in melanophores
• Spatio-temporal modelling of the Hes1 and p53-Mdm2 intracellular signalling pathways
• ``Classical electropermeabilization modeling at the cell scale

Cited in

(6)

• A continuum mechanics model of enzyme-based tissue degradation in cancer therapies
• Modeling the early steps of cytoplasmic trafficking in viral infection and gene delivery
• The kinetics of vitamin D\(_3\) in the osteoblastic cell
• Effective Motion of a Virus Trafficking Inside a Biological Cell
• Diffusion in an elastic medium: a model for macromolecule transport across the nuclear pore complex
• Modeling of the kinetics of vitamin \(\text{D}_3\) in osteoblastic cells

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