Hopf Bifurcations of Reaction Networks with Zero-One Stoichiometric Coefficients

DOI10.1137/22M1519754zbMATH Open1522.92027arXiv2208.04196OpenAlexW4385951804MaRDI QIDQ6076409FDOQ6076409

Authors: Xiaoxian Tang 

Publication date: 21 September 2023

Published in: SIAM Journal on Applied Dynamical Systems (Search for Journal in Brave)

Abstract: For the reaction networks with zero-one stoichiometric coefficients (or simply zero-one networks), we prove that if a network admits a Hopf bifurcation, then the rank of the stoichiometric matrix is at least four. As a corollary, we show that if a zero-one network admits a Hopf bifurcation, then it contains at least four species and five reactions. As applications, we show that there exist rank-four subnetworks, which have the capacity for Hopf bifurcations/oscillations, in two biologically significant networks: the MAPK cascades and the ERK network. We provide a computational tool for computing all four-species, five-reaction, zero-one networks that have the capacity for Hopf bifurcations.

Full work available at URL: https://arxiv.org/abs/2208.04196

Recommendations

• The smallest bimolecular mass action reaction networks admitting Andronov–Hopf bifurcation
• Complete set of Hopf bifurcation in an autocatalytic ring network
• Detection of Hopf bifurcations in chemical reaction networks using convex coordinates
• Efficient methods to compute Hopf bifurcations in chemical reaction networks using reaction coordinates
• Computing Hopf bifurcations in chemical reaction networks using reaction coordinates

zbMATH Keywords

Hopf bifurcationoscillationmass-action kineticsbiochemical reaction network

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42) Bifurcation theory for ordinary differential equations (34C23) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Cites Work

• MATCONT
• Elements of applied bifurcation theory
• Deciding Hopf bifurcations by quantifier elimination in a software-component architecture
• Detection of Hopf bifurcations in chemical reaction networks using convex coordinates
• Title not available (Why is that?)
• Smallest chemical reaction system with Hopf bifurcation
• Generalized form of Hurwitz-Routh criterion and Hopf bifurcation of higher order
• Foundations of chemical reaction network theory
• Oscillations and bistability in a model of ERK regulation
• Multistationarity in Biochemical Networks: Results, Analysis, and Examples
• On the existence of Hopf bifurcations in the sequential and distributive double phosphorylation cycle
• Inheritance of oscillation in chemical reaction networks
• Multistability of small reaction networks
• Monomolecular reaction networks: flux-influenced sets and balloons
• The smallest bimolecular mass action reaction networks admitting Andronov–Hopf bifurcation
• Splitting Reactions Preserves Nondegenerate Behaviors in Chemical Reaction Networks

Cited In (8)

• Title not available (Why is that?)
• Classification of infinitesimal homeostasis in four-node input-output networks
• Combinatorial approaches to Hopf bifurcations in systems of interacting elements
• Efficient methods to compute Hopf bifurcations in chemical reaction networks using reaction coordinates
• The smallest bimolecular mass action reaction networks admitting Andronov–Hopf bifurcation
• Prevalence of Multistationarity and Absolute Concentration Robustness in Reaction Networks
• Detection of Hopf bifurcations in chemical reaction networks using convex coordinates
• Symbolic Proof of Bistability in Reaction Networks

This page was built for publication: Hopf Bifurcations of Reaction Networks with Zero-One Stoichiometric Coefficients

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q6076409)