Direct estimation of parameters in ODE models using WENDy: weak-form estimation of nonlinear dynamics
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Publication:6078313
Abstract: We introduce the Weak-form Estimation of Nonlinear Dynamics (WENDy) method for estimating model parameters for non-linear systems of ODEs. Without relying on any numerical differential equation solvers, WENDy computes accurate estimates and is robust to large (biologically relevant) levels of measurement noise. For low dimensional systems with modest amounts of data, WENDy is competitive with conventional forward solver-based nonlinear least squares methods in terms of speed and accuracy. For both higher dimensional systems and stiff systems, WENDy is typically both faster (often by orders of magnitude) and more accurate than forward solver-based approaches. The core mathematical idea involves an efficient conversion of the strong form representation of a model to its weak form, and then solving a regression problem to perform parameter inference. The core statistical idea rests on the Errors-In-Variables framework, which necessitates the use of the iteratively reweighted least squares algorithm. Further improvements are obtained by using orthonormal test functions, created from a set of C-infinity bump functions of varying support sizes. We demonstrate the high robustness and computational efficiency by applying WENDy to estimate parameters in some common models from population biology, neuroscience, and biochemistry, including logistic growth, Lotka-Volterra, FitzHugh-Nagumo, Hindmarsh-Rose, and a Protein Transduction Benchmark model. Software and code for reproducing the examples is available at (https://github.com/MathBioCU/WENDy).
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Cites work
- A joint estimation approach to sparse additive ordinary differential equations
- A new method for the identification of systems
- A Spline Least Squares Method for Numerical Parameter Estimation in Differential Equations
- An analysis of variance test for normality (complete samples)
- Discovering governing equations from data by sparse identification of nonlinear dynamical systems
- Distributions
- Estimation of ordinary differential equation parameters using constrained local polynomial regression
- Estimation techniques for distributed parameter systems
- EXPLICIT ESTIMATION OF DERIVATIVES FROM DATA AND DIFFERENTIAL EQUATIONS BY GAUSSIAN PROCESS REGRESSION
- Generalized sensitivity functions for size-structured population models
- Generation of Finite Difference Formulas on Arbitrarily Spaced Grids
- scientific article; zbMATH DE number 1734139 (Why is no real title available?)
- scientific article; zbMATH DE number 3997615 (Why is no real title available?)
- scientific article; zbMATH DE number 3056109 (Why is no real title available?)
- Learning mean-field equations from particle data using WSINDy
- Learning sparse nonlinear dynamics via mixed-integer optimization
- Parameter estimation for differential equation models using a framework of measurement error in regression models
- Parameter Estimation for Differential Equations: a Generalized Smoothing Approach
- Parameter estimation of ODE's via nonparametric estimators
- Parametric estimation of ordinary differential equations with orthogonality conditions
- Quasi-maximum likelihood estimation and inference in dynamic models with time-varying covariances
- Robust and optimal sparse regression for nonlinear PDE models
- Spatial Regression With Partial Differential Equation Regularisation
- Spatiotemporal system identification on nonperiodic domains using Chebyshev spectral operators and system reduction algorithms
- Spatiotemporal system reconstruction using Fourier spectral operators and structure selection techniques
- Statistical properties of the Hough transform estimator in the presence of measurement errors
- The influence of numerical error on parameter estimation and uncertainty quantification for advective PDE models
- Variational system identification of the partial differential equations governing the physics of pattern-formation: inference under varying fidelity and noise
- Weak SINDy for partial differential equations
- Weak SINDy: Galerkin-based data-driven model selection
Cited in
(8)- Asymptotic consistency of the WSINDy algorithm in the limit of continuum data
- An efficient first-order conditional gradient algorithm in data-driven sparse identification of nonlinear dynamics to solve sparse recovery problems under noise
- Influence of initial conditions on data-driven model identification and information entropy for ideal MHD problems
- A constrained optimisation framework for parameter identification of the SIRD model
- Physics-informed active learning with simultaneous weak-form latent space dynamics identification
- A practical identifiability criterion leveraging weak-form parameter estimation
- Weak form scientific machine learning: test function construction for system identification
- Inferring constitutive forces from noisy Allen-Cahn movies with moment equations
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