Order-of-mutation effects on cancer progression: models for myeloproliferative neoplasm

DOI10.1007/S11538-024-01257-5MaRDI QIDQ6192539zbMATH OpenOpenAlexFDO

Authors

Publication date 11 March 2024

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://arxiv.org/abs/2308.09941

zbMATH Keywords

cancergene expressionbistabilityMoran processmutation order

Mathematics Subject Classification ID

Nonlinear ordinary differential equations and systems (34A34) Pathology, pathophysiology (92C32)

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Cites work

• Cancer-induced immunosuppression can enable effectiveness of immunotherapy through bistability generation: a mathematical and computational examination
• Fixation times in differentiation and evolution in the presence of bottlenecks, deserts, and oases
• Inference on autoregulation in gene expression with variance-to-mean ratio
• Inference on the structure of gene regulatory networks
• Mathematical representation of Clausius' and Kelvin's statements of the second law and irreversibility
• Simple mathematical models of gene regulatory dynamics
• Two-layer mathematical modeling of gene expression: incorporating DNA-level information and system dynamics

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