Order-of-mutation effects on cancer progression: models for myeloproliferative neoplasm

DOI10.1007/S11538-024-01257-5arXiv2308.09941OpenAlexW4386080934MaRDI QIDQ6192539FDOQ6192539

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Publication date: 11 March 2024

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/2308.09941

zbMATH Keywords

cancergene expressionbistabilityMoran processmutation order

Mathematics Subject Classification ID

Nonlinear ordinary differential equations and systems (34A34) Pathology, pathophysiology (92C32)

Cites Work

• Fixation times in differentiation and evolution in the presence of bottlenecks, deserts, and oases
• Inference on the structure of gene regulatory networks
• Two-layer mathematical modeling of gene expression: incorporating DNA-level information and system dynamics
• Inference on autoregulation in gene expression with variance-to-mean ratio
• Simple mathematical models of gene regulatory dynamics
• Mathematical representation of Clausius' and Kelvin's statements of the second law and irreversibility
• Cancer-induced immunosuppression can enable effectiveness of immunotherapy through bistability generation: a mathematical and computational examination

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