Haldane linearisation done right: solving the nonlinear recombination equation the easy way

DOI10.3934/DCDS.2016088zbMATH Open1353.92064arXiv1606.05175OpenAlexW2964007117MaRDI QIDQ727402FDOQ727402

Authors: Ellen Baake, Michael Baake 

Publication date: 6 December 2016

Published in: Discrete and Continuous Dynamical Systems (Search for Journal in Brave)

Abstract: The nonlinear recombination equation from population genetics has a long history and is notoriously difficult to solve, both in continuous and in discrete time. This is particularly so if one aims at full generality, thus also including degenerate parameter cases. Due to recent progress for the continuous time case via the identification of an underlying stochastic fragmentation process, it became clear that a direct general solution at the level of the corresponding ODE itself should also be possible. This paper shows how to do it, and how to extend the approach to the discrete-time case as well.

Full work available at URL: https://arxiv.org/abs/1606.05175

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zbMATH Keywords

population geneticsclosed solutionmeasure-valued equationscontinuous and discrete timenonlinear recombination equation

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Nonlinear differential equations in abstract spaces (34G20) Discrete version of topics in analysis (39A12) Complete lattices, completions (06B23)

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Cited In (15)

• The evolution of a population under recombination: how to linearise the dynamics
• Embedding of Markov matrices for \(d \leqslant 4\)
• Labeled partitions in action: recombination, selection, mutation and more
• Solving the migration-recombination equation from a genealogical point of view
• Nonlinear recombinations and generalized random transpositions
• Single-crossover recombination in discrete time
• Solving the selection-recombination equation: ancestral lines and dual processes
• Selection, recombination, and the ancestral initiation graph
• Mutation and recombination with tight linkage
• Lines of descent in the deterministic mutation-selection model with pairwise interaction
• Asymptotic sampling distributions made easy: loose linkage in the ancestral recombination graph
• Genetic recombination as a generalised gradient flow
• The recombination equation for interval partitions
• Notes on Markov embedding
• Recombination semigroups on measure spaces

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