Modeling gene regulatory networks with piecewise linear differential equations

DOI10.1016/J.EJOR.2005.11.044zbMATH Open1124.92008OpenAlexW2140154342MaRDI QIDQ877598FDOQ877598

Jutta Gebert, Gerhard-Wilhelm Weber, Nicole Radde

Publication date: 3 May 2007

Published in: European Journal of Operational Research (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.ejor.2005.11.044

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zbMATH Keywords

computational biologydynamical systemoptimization problemgene regulationsystem of piecewise linear differential equations

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Biochemistry, molecular biology (92C40) Discontinuous ordinary differential equations (34A36) Cell biology (92C37)

Cites Work

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Cited In (36)

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• Qualitative simulation of genetic regulatory networks using piecewise-linear models
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• Formal analysis of oscillatory behaviors in biological regulatory networks: an alternative approach
• Hybrid Systems: Computation and Control
• Probabilistic analysis of a class of compartmental models formulated by random differential equations
• Vine copula graphical models in the construction of biological networks
• Nonlinear control designs and their application to cancer differentiation therapy
• Optimization of gene-environment networks in the presence of errors and uncertainty with Chebychev approximation
• Polynomial representations of piecewise-linear differential equations arising from gene regulatory networks
• Title not available (Why is that?)
• Loop-based conic multivariate adaptive regression splines is a novel method for advanced construction of complex biological networks
• Title not available (Why is that?)
• Time-delayed models of gene regulatory networks
• Modeling nonlinear dynamic biological systems with human-readable fuzzy rules optimized by convergent heterogeneous particle swarm
• Robust \(H_\infty\) control of discrete switched system with time delay
• An algorithmic approach to analyse genetic networks and biological energy production: an introduction and contribution where OR meets biology†
• Comparing different ODE modelling approaches for gene regulatory networks
• Numerical simulation of piecewise-linear models of gene regulatory networks using complementarity systems
• The transition from differential equations to Boolean networks: A case study in simplifying a regulatory network model
• A survey on piecewise-linear models of regulatory dynamical systems
• Using a linear differential model for regulatory networks of genes related to breast cancer metastasis
• Modeling and simulation of nitrogen regulation in corynebacterium glutamicum
• Modern tools for the time-discrete dynamics and optimization of gene-environment networks
• On generalized semi-infinite optimization of genetic networks
• On the analysis of a dynamical model representing gene regulatory networks under negative feedback
• MARS as an alternative approach of Gaussian graphical model for biochemical networks
• Numerical analysis of a method for a partial integro-differential equation model in regulatory gene networks
• On optimization, dynamics and uncertainty: A tutorial for gene-environment networks
• A mathematical program to refine gene regulatory networks
• New stability conditions for GRNs with neutral delay
• Modeling, inference and optimization of regulatory networks based on time series data
• On the use of the Hill functions in mathematical models of gene regulatory networks
• Coarse-grained optimization-driven design and piecewise linear modeling of synthetic genetic circuits
• Rumour propagation: an operational research approach by computational and information theory
• Local Identification of Piecewise Deterministic Models of Genetic Networks

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