Stationary mutant distributions and evolutionary optimization

The Eigen-Schuster kinetic theory of polynucleotide evolution is modified for the case that mutations are no more rare events. It is found that the fitness is then no longer the property of single types but depends critically on the efficiency of their nearest neighbours.

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Evolution with State-Dependent Mutations
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Stationary distributions under mutation-selection balance: structure and properties
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Cites work

A stochastic theory of macromolecular evolution
Demographic Parameters and Natural Selection
scientific article; zbMATH DE number 3657493 (Why is no real title available?)
scientific article; zbMATH DE number 3239038 (Why is no real title available?)
On Eigen's theory of the self-organization of matter and the evolution of biological macromolecules
On the theory of selection of coupled macromolecular systems
Polynucleotide evolution and branching processes
Some principles governing selection in self-reproducing macromolecular systems. An analog of Fisher's fundamental theorem
Spectral properties of Eigen evolution matrices
Stochastic analysis of a nonlinear model for selection of biological macromolecules

Cited in

(36)

Handicapped individua in evolutionary processes
Evolution in a flat fitness landscape
Complementary replication
Mutation in autocatalytic reaction networks. An analysis based on perturbation theory
Optimization by hierarchical mutant production
Dynamics of small autocatalytic reaction networks. II: Replication, mutation and catalysis
Biological evolution model with conditional mutation rates
On the application of statistical physics to evolutionary biology
A trade-off between neutrality and adaptability limits the optimization of viral quasispecies
A numerical approach to determine mutant invasion fitness and evolutionary singular strategies
Error thresholds for self- and cross-specific enzymatic replication
Simple quasispecies models for the survival-of-the-flattest effect: the role of space
Optimal mutation probability for genetic algorithms
A theory of evolution that includes prebiotic self-organization and episodic species formation
A modified Crow-Kimura evolution model with reduced fitness for the smooth distribution of population
Mutation landscapes
Semiconservative quasispecies equations for polysomic genomes: the haploid case
Selection for mutational robustness in finite populations
Evolutionary coupling between the deleteriousness of gene mutations and the amount of non-coding sequences
Variations in polymer fitness at elevated mutation rates
On the behavior of the leading eigenvalue of Eigen's evolutionary matrices
Stochastic modeling and simulation of viral evolution
Hebbian crosstalk and input segregation
Characteristic time in quasispecies evolution
Quasispecies dynamics with network constraints
On Eigen's quasispecies model, two-valued fitness landscapes, and isometry groups acting on finite metric spaces
scientific article; zbMATH DE number 3854861 (Why is no real title available?)
Linear algebra of the permutation invariant Crow-Kimura model of prebiotic evolution
Stochastic Populations, Power Law and Fitness Aggregation in Genetic Algorithms
scientific article; zbMATH DE number 2214464 (Why is no real title available?)
Entropic contribution to phenotype fitness
Variation approach to error threshold in generic fitness landscape
The Crow-Kimura evolution model in case of asymmetric mutation and recombination
Karlin-McGregor mutational occupancy problem revisited
First and second moments and the mean Hamming distance in a stochastic replication-mutation model for biological macromolecules
Quasispecies and recombination

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