Mathematical approaches to optimization of cancer chemotherapy

DOI10.1007/BF02460814zbMath0404.92004OpenAlexW4231074347WikidataQ41726846 ScholiaQ41726846MaRDI QIDQ1256971

S. Zietz, Claudio Nicolini

Publication date: 1979

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/bf02460814

zbMATH Keywords

Optimal Control TheoryCancer ChemotherapyCellular GrowthGompertzian Type ModelOptimal Durations of TreatmentPareto Optimality Conditions

Mathematics Subject Classification ID

Medical applications (general) (92C50) Optimality conditions for problems involving ordinary differential equations (49K15)

Related Items (20)

Chemotherapeutic treatments: A study of the interplay among drug resistance, toxicity and recuperation from side effects ⋮ Conflicting objectives in chemotherapy with drug resistance ⋮ Optimal control of cancer chemotherapy with delays and state constraints ⋮ On strategies on a mathematical model for leukemia therapy ⋮ Optimal control for a cancer chemotherapy problem with general growth and loss functions ⋮ Role of optimal control theory in cancer chemotherapy ⋮ Solution of the feedback control problem in the mathematical model of leukaemia therapy ⋮ A survey of optimization models on cancer chemotherapy treatment planning ⋮ Optimal control in some cancer chemotherapy problems ⋮ Optimization of Radiation Therapy Fractionation Schedules in the Presence of Tumor Repopulation ⋮ Chemotherapeutic treatments involving drug resistance and level of normal cells as a criterion of toxicity ⋮ Cancer chemotherapy: Optimal control using the Verhulst-Pearl equation ⋮ Optimal control applications in biomedical engineering-a survey ⋮ Kinetics of deterrence of Gompertzian growth ⋮ A kinetic study of chemotherapy ⋮ Mathematical model of cancer chemotherapy. Periodic schedules of phase- specific cytotoxic-agent administration increasing the selectivity of therapy ⋮ Model predictive tumour volume control using nonlinear optimization ⋮ Analyzing the quality robustness of chemotherapy plans with respect to model uncertainties ⋮ Resonance phenomena in cell population chemotherapy models ⋮ Application of optimal control theory to analysis of cancer chemotherapy regimens

Cites Work

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• Linear multiobjective programming
• A theoretical and computational method for determining optimal treatment schedules in fractionated radiation therapy
• Optimal control analysis in the chemotherapy of IgG multiple myeloma
• Nondominated decisions and cone convexity in dynamic multicriteria decision problems
• A method of unconstrained global optimization
• Tumor growth and chemotherapy: Mathematical methods, computer simulations, and experimental foundations

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