Parameter regions that give rise to \(2\lfloor \frac{n}{2} \rfloor +1\) positive steady states in the \(n\)-site phosphorylation system

DOI10.3934/MBE.2019381zbMath1467.92075arXiv1904.11633OpenAlexW2969978949WikidataQ91168018 ScholiaQ91168018MaRDI QIDQ2045560

Rick Rischter, Mercedes Pérez Millán, Magalí Giaroli, Alicia Dickenstein

Publication date: 13 August 2021

Published in: Mathematical Biosciences and Engineering (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1904.11633

zbMATH Keywords

steady statesmultistationaritydistributive sequential \(n\)-site phosphorylation/dephosphorylation systemintermediate speciesregions of multistationarity

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40)

Related Items (5)

The steady-state degree and mixed volume of a chemical reaction network ⋮ Families of polynomials in the study of biochemical reaction networks ⋮ Dynamics of ERK regulation in the processive limit ⋮ Parameter Region for Multistationarity in \({\boldsymbol{n-}}\)Site Phosphorylation Networks ⋮ Lower bounds for positive roots and regions of multistationarity in chemical reaction networks

Uses Software

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• Multistationarity in sequential distributed multisite phosphorylation networks
• Power-Law Kinetics and Determinant Criteria for the Preclusion of Multistationarity in Networks of Interacting Species
• The Structure of MESSI Biological Systems
• A Polyhedral Method for Sparse Systems with Many Positive Solutions
• A proof of unlimited multistability for phosphorylation cycles

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