Mixture of linear mixed models for clustering gene expression profiles from repeated microarray experiments

DOI10.1191/1471082X05st096oazbMath1111.62103MaRDI QIDQ3413106

Christian Lavergne, Gilles Celeux, Olivier C. Martin

Publication date: 3 January 2007

Published in: Statistical Modelling (Search for Journal in Brave)

zbMATH Keywords

random effectslinear modelscluster analysismixture modelspenalized likelihood criteria

Mathematics Subject Classification ID

Classification and discrimination; cluster analysis (statistical aspects) (62H30) Applications of statistics to biology and medical sciences; meta analysis (62P10) Linear inference, regression (62J99) Biochemistry, molecular biology (92C40)

Related Items

Clustering longitudinal profiles using P-splines and mixed effects models applied to time-course gene expression data ⋮ Mixture models for clustering multilevel growth trajectories ⋮ Comparison of the EM, CEM and SEM algorithms in the estimation of finite mixtures of linear mixed models: a simulation study ⋮ A mixture model-based approach to the clustering of exponential repeated data ⋮ An evaluation of a novel approach for clustering genes with dissimilar replicates ⋮ Clustering of short time-course gene expression data with dissimilar replicates ⋮ Linear mixed models with marginally symmetric nonparametric random effects ⋮ Mixtures of spatial spline regressions for clustering and classification ⋮ Unsupervised learning of mixture regression models for longitudinal data ⋮ A statistical test for detecting parent-of-origin effects when parental information is missing ⋮ Spatial clustering of time series via mixture of autoregressions models and Markov random fields ⋮ Extending finite mixtures of \(t\) linear mixed-effects models with concomitant covariates ⋮ Robust clustering of COVID-19 cases across U.S. counties using mixtures of asymmetric time series models with time varying and freely indexed covariates ⋮ Finite mixture of censored linear mixed models for irregularly observed longitudinal data ⋮ Classification based on multivariate mixed type longitudinal data with an application to the EU-SILC database ⋮ Clusterwise multivariate regression of mixed-type panel data ⋮ Clustering for multivariate continuous and discrete longitudinal data ⋮ Maximum Pseudolikelihood Estimation for Model-Based Clustering of Time Series Data ⋮ Gene profiling for determining pluripotent genes in a time course microarray experiment ⋮ Model-Based Clustering of Longitudinal Data: Application to Modeling Disease Course and Gene Expression Trajectories ⋮ Mixture of multivariate \(t\) nonlinear mixed models for multiple longitudinal data with heterogeneity and missing values ⋮ Markov and Semi-Markov Switching Linear Mixed Models Used to Identify Forest Tree Growth Components ⋮ A Tailored Multivariate Mixture Model for Detecting Proteins of Concordant Change Among Virulent Strains of Clostridium Perfringens ⋮ Bayesian clustering of replicated time-course gene expression data with weak signals ⋮ Clustering Using Objective Functions and Stochastic Search ⋮ Clustering in linear mixed models with approximate Dirichlet process mixtures using EM algorithm ⋮ Mixture of linear mixed models using multivariatetdistribution ⋮ Model-based clustering for longitudinal data ⋮ Random effects mixture models for clustering electrical load series ⋮ Simultaneous fixed and random effects selection in finite mixture of linear mixed-effects models ⋮ Clustering in linear-mixed models with a group fused lasso penalty ⋮ An Alternative Estimation Approach for the Heterogeneity Linear Mixed Model ⋮ Mixtures of stochastic differential equations with random effects: application to data clustering

Cites Work

• Choosing starting values for the EM algorithm for getting the highest likelihood in multivariate Gaussian mixture models
• Estimating the dimension of a model
• Optimization of mixture models: Comparison of different strategies
• How Many Clusters? Which Clustering Method? Answers Via Model-Based Cluster Analysis
• Importance of replication in microarray gene expression studies: Statistical methods and evidence from repetitive cDNA hybridizations
• Conditional Akaike information for mixed-effects models
• Gaussian model selection
• A new look at the statistical model identification