Toxicity in sequential dose-response experiments

DOI10.1080/07474949508836333zbMath0838.62063OpenAlexW2059810752MaRDI QIDQ4865163

William F. Rosenberger, Nancy Flournoy, Stephen D. Durham

Publication date: 6 June 1996

Published in: Sequential Analysis (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/07474949508836333

zbMATH Keywords

Markov chainsadaptive designssequential allocationdichotomous responsesdose-response studiesquantile targetingrandomized up-and-down designstotal number of toxic responses

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05)

Related Items (7)

Adaptive clinical trial designs for phase I cancer studies ⋮ Group up-and-down designs for dose-finding ⋮ Up-and-Down Designs for Selecting the Dose with Maximum Success Probability ⋮ Dose Finding Using the Biased Coin Up-and-Down Design and Isotonic Regression ⋮ Derivation of Exact Distributions Following an Up-and-Down Design ⋮ Optimizing a Unimodal Response Function for Binary Variables ⋮ An Optimizing Up-and-Down Design

Cites Work

• A Method for Obtaining and Analyzing Sensitivity Data
• Unnamed Item

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