A comparison of methods for adaptive treatment selection

DOI10.1002/BIMJ.200710453MaRDI QIDQ5123111zbMATH OpenOpenAlexWikidataFDO

Authors Tim Friede, Nigel Stallard

Publication date 25 September 2020

Published in Biometrical Journal (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1002/bimj.200710453

zbMATH Keywords

adaptive designsclinical trialsdunnett testsequential designstreatment selection

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cited in

(15)

• A comparison of methods for constructing confidence intervals after phase II/III clinical trials
• Parameter estimation following an adaptive treatment selection trial design
• Confirmatory seamless phase II/III clinical trials with hypotheses selection at interim: general concepts
• Adaptive seamless clinical trials using early outcomes for treatment or subgroup selection: methods, simulation model and their implementation in R
• scientific article; zbMATH DE number 7745094 (Why is no real title available?)
• Improving adaptive seamless designs through Bayesian optimization
• A conditional error function approach for adaptive enrichment designs with continuous endpoints
• Adaptive multiarm multistage clinical trials
• Statistical tests for two-stage adaptive seamless design using short- and long-term binary outcomes
• Flexible selection of a single treatment incorporating short-term endpoint information in a phase II/III clinical trial
• Flexible sequential designs for multi-arm clinical trials
• Planning multi-arm screening studies within the context of a drug development program
• Precision of maximum likelihood estimation in adaptive designs
• Twenty-five years of confirmatory adaptive designs: opportunities and pitfalls
• A comparison of methods for treatment selection in seamless phase II/III design

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