Modular decomposition of metabolic systems via null-space analysis

DOI10.1016/J.JTBI.2007.08.005MaRDI QIDQ2216371zbMATH OpenOpenAlexWikidataFDO

Authors Mark G. Poolman, Cristiana Sebu, Michael Pidcock, David A. Fell

Publication date 15 December 2020

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://radar.brookes.ac.uk/radar/items/efc113f1-37dc-0621-c096-f03e7c84ced5/1

zbMATH Keywords

dendrogramflux correlation coefficientgenome scalemetabolic modelnull-space

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42) Genetics and epigenetics (92D10)

Recommendations

• Systemic metabolic reactions are obtained by singular value decomposition of genome-scale stoichiometric matrices
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Cites work

• scientific article; zbMATH DE number 1090658 (Why is no real title available?)
• Monte Carlo sampling and principal component analysis of flux distributions yield topological and modular information on metabolic networks
• Non-uniqueness and Inversions in Cluster Analysis

Cited in

(4)

• Systemic metabolic reactions are obtained by singular value decomposition of genome-scale stoichiometric matrices
• Monte Carlo sampling and principal component analysis of flux distributions yield topological and modular information on metabolic networks
• A strong connectivity decomposition method for analyzing the multi-equilibrium property of general metabolic networks
• Structural conserved moiety splitting of a stoichiometric matrix

Describes a project that uses

Uses Software

• Metatool
• ScrumPy

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