The relationships between message passing, pairwise, Kermack-McKendrick and stochastic SIR epidemic models
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Abstract: We consider a very general stochastic model for an SIR epidemic on a network which allows an individual's infectious period, and the time it takes to contact each of its neighbours after becoming infected, to be correlated. We write down the message passing system of equations for this model and prove, for the first time, that it has a unique feasible solution. We also generalise an earlier result by proving that this solution provides a rigorous upper bound for the expected epidemic size (cumulative number of infection events) at any fixed time . We specialise these results to a homogeneous special case where the graph (network) is symmetric. The message passing system here reduces to just four equations. We prove that cycles in the network inhibit the spread of infection, and derive important epidemiological results concerning the final epidemic size and threshold behaviour for a major outbreak. For Poisson contact processes, this message passing system is equivalent to a non-Markovian pair approximation model, which we show has well-known pairwise models as special cases. We show further that a sequence of message passing systems, starting with the homogeneous one just described, converges to the deterministic Kermack-McKendrick equations for this stochastic model. For Poisson contact and recovery, we show that this convergence is monotone, from which it follows that the message passing system (and hence also the pairwise model) here provides a better approximation to the expected epidemic size at time than the Kermack-McKendrick model.
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Cited in
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- Mean-field models for non-Markovian epidemics on networks
- Pairwise approximation for SIR-type network epidemics with non-Markovian recovery
- A nonstandard finite difference scheme for the SVICDR model to predict COVID-19 dynamics
- Solvability of implicit final size equations for SIR epidemic models
- A SIR-based model for contact-based messaging applications supported by permanent infrastructure
- The deterministic Kermack-McKendrick model bounds the general stochastic epidemic
- Transmission dynamics of a two-strain pairwise model with infection age
- Spreading of infection on temporal networks: an edge-centered, contact-based perspective
- Epidemic model on a network: analysis and applications to COVID-19
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