A stochastic model for a single click of Muller's ratchet

DOI10.1016/J.JTBI.2010.03.014MaRDI QIDQ1719902zbMATH OpenOpenAlexWikidataFDO

Authors Xianqiang Yang

Publication date 12 February 2019

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2010.03.014

zbMATH Keywords

asexual populationrandom genetic drifttheoretical population geneticsMuller's ratchet

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Problems related to evolution (92D15)

Recommendations

• How often does the ratchet click? Facts, heuristics, asymptotics
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• The accumulation of mutations in asexual populations and the structure of genealogical trees in the presence of selection

Cites work

• scientific article; zbMATH DE number 3954718 (Why is no real title available?)
• Diffusion models in population genetics
• Fixation at a locus with multiple alleles: structure and solution of the Wright Fisher model
• How often does the ratchet click? Facts, heuristics, asymptotics
• On Quasi-Stationary distributions in absorbing discrete-time finite Markov chains
• Singular solutions of the diffusion equation of population genetics
• The Adequacy of the Diffusion Approximation to Certain Distributions in Genetics
• The accumulation of deleterious genes in a population - Muller's Ratchet
• The traveling-wave approach to asexual evolution: Muller's ratchet and speed of adaptation

Cited in

(12)

• Quasi-equilibria and click times for a variant of Muller's ratchet
• Mutational meltdown in asexual populations doomed to extinction
• The influence of genetic drift on the formation and stability of polymorphisms arising from negative frequency-dependent selection
• Two linked loci under mutation-selection balance and Muller's ratchet
• An informational transition in conditioned Markov chains: applied to genetics and evolution
• Extinction scenarios in evolutionary processes: a multinomial Wright-Fisher approach
• Muller's ratchet clicks in finite time
• Fluctuations in fitness distributions and the effects of weak linked selection on sequence evolution
• Discrete–time ratchets, the Fokker–Planck equation and Parrondo's paradox
• How often does the ratchet click? Facts, heuristics, asymptotics
• Effect of drift, selection and recombination on the equilibrium frequency of deleterious mutations
• Diffusion approximations in population genetics and the rate of Muller's ratchet

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