Mathematical analysis of the pharmacokinetic-pharmacodynamic (PKPD) behaviour of monoclonal antibodies: predicting \textit{in vivo} potency
DOI10.1016/J.JTBI.2011.04.030zbMATH Open1397.92270OpenAlexW2163848645WikidataQ51570544 ScholiaQ51570544MaRDI QIDQ1783553FDOQ1783553
Authors: Philip J. Aston, Gianne Derks, A. Raji, Balaji M. Agoram, Piet H. van der Graaf 
Publication date: 21 September 2018
Published in: Journal of Theoretical Biology (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1016/j.jtbi.2011.04.030
Recommendations
- Mathematical modeling of antibody drug conjugates with the target and tubulin dynamics to predict AUC
- A mathematical study of effects of delays arising from the interaction of anti-drug antibody and therapeutic protein in the immune response system
- Mathematical modeling of humoral immune response suppression by passively administered antibodies in mice
- Mathematics of pharmacokinetics and pharmacodynamics: diversity of topics, models and methods
- A mathematical model of antibody-dependent cellular cytotoxicity (ADCC)
- Development and Validation of a Mathematical Model to Describe Anti-Cancer Prodrug Activation by Antibody-Enzyme Conjugates
- scientific article; zbMATH DE number 4077009
- Modelling random antibody adsorption and immunoassay activity
- Experimental data and PBPK modeling quantify antibody interference in PEGylated drug carrier delivery
- Pharmacokinetics: ODE and statistical model choice
Medical applications (general) (92C50) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)
Cited In (14)
- A mathematical analysis of rebound in a target-mediated drug disposition model. I: Without feedback
- Network biology in development of monoclonal antibody therapeutics
- Challenges in pharmacology modelling
- A mathematical analysis of rebound in a target-mediated drug disposition model. II. With feedback
- Dynamics of target-mediated drug disposition: how a drug reaches its target
- Asymptotic analysis of a target-mediated drug disposition model: algorithmic and traditional approaches
- Topics in mathematical pharmacology
- Mathematical modeling of antibody drug conjugates with the target and tubulin dynamics to predict AUC
- Cross-membrane signal transduction of receptor tyrosine kinases (RTKs): from systems biology to systems pharmacology
- Global dynamics of target-mediated drug disposition models and their solutions by nonstandard finite difference method
- Geometric singular perturbation analysis of a dynamical target mediated drug disposition model
- Dynamics of antibody binding and neutralization during viral infection
- Slow invariant manifolds of fast-slow systems of ODEs with physics-informed neural networks
- An importance sampling approach for reliable and efficient inference in Bayesian ordinary differential equation models
This page was built for publication: Mathematical analysis of the pharmacokinetic-pharmacodynamic (PKPD) behaviour of monoclonal antibodies: predicting \textit{in vivo} potency
Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q1783553)
