Mathematical analysis of the pharmacokinetic-pharmacodynamic (PKPD) behaviour of monoclonal antibodies: predicting \textit{in vivo} potency

DOI10.1016/j.jtbi.2011.04.030zbMath1397.92270WikidataQ51570544 ScholiaQ51570544MaRDI QIDQ1783553

Piet H. van der Graaf, Gianne Derks, Philip J. Aston, Adewale Raji, Balaji M. Agoram

Publication date: 21 September 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2011.04.030

zbMATH Keywords

affinity; efficacy; target-mediated drug disposition; pharmacology; IgE

Mathematics Subject Classification ID

92C45: Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.)

92C50: Medical applications (general)