A mathematical analysis of rebound in a target-mediated drug disposition model. I: Without feedback
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Publication:2447559
DOI10.1007/s00285-013-0675-5zbMath1284.92037OpenAlexW2033399761WikidataQ45937545 ScholiaQ45937545MaRDI QIDQ2447559
Piet H. van der Graaf, Gianne Derks, Balaji M. Agoram, Philip J. Aston
Publication date: 28 April 2014
Published in: Journal of Mathematical Biology (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1007/s00285-013-0675-5
Dynamical systems in biology (37N25) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50) Qualitative investigation and simulation of ordinary differential equation models (34C60)
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Cites Work
- Dynamics of target-mediated drug disposition: how a drug reaches its target
- Geometric singular perturbation theory for ordinary differential equations
- Mathematical analysis of the pharmacokinetic-pharmacodynamic (PKPD) behaviour of monoclonal antibodies: predicting \textit{in vivo} potency
- A mathematical analysis of rebound in a target-mediated drug disposition model. II. With feedback
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