Analysis of mass-action systems by split network translation
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Publication:2072227
DOI10.1007/S10910-021-01299-3zbMATH Open1481.92191arXiv2104.03454OpenAlexW3216540893MaRDI QIDQ2072227FDOQ2072227
Authors: Matthew D. Johnston 
Publication date: 26 January 2022
Published in: Journal of Mathematical Chemistry (Search for Journal in Brave)
Abstract: We introduce the notion of corresponding a chemical reaction network to a split network translation, and use this novel process to extend the scope of existing network-based theory for characterizing the steady state set of mass-action systems. In the process of network splitting, the reactions of a network are divided into subnetworks, called slices, in such a way that, when summed across the slices, the stoichiometry of each reaction sums to that of the original network. This can produce a network with more desirable structural properties, such as weak reversibility and a lower deficiency, which can then be used to establish steady state properties of the original mass-action system such as multistationarity and absolute concentration robustness. We also present a computational implementation utilizing mixed-integer linear programming for determining whether a given chemical reaction network has a weakly reversible split network translation.
Full work available at URL: https://arxiv.org/abs/2104.03454
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Cited In (6)
- Structural conserved moiety splitting of a stoichiometric matrix
- Splitting Reactions Preserves Nondegenerate Behaviors in Chemical Reaction Networks
- Translated chemical reaction networks
- Network translation and steady-state properties of chemical reaction systems
- Computational Translation Framework Identifies Biochemical Reaction Networks with Special Topologies and Their Long-Term Dynamics
- A computational approach to steady state correspondence of regular and generalized mass action systems
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