Translated chemical reaction networks
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Publication:458720
DOI10.1007/S11538-014-9947-5zbMATH Open1297.92096arXiv1305.5845OpenAlexW3100811169WikidataQ51103659 ScholiaQ51103659MaRDI QIDQ458720FDOQ458720
Authors: Matthew D. Johnston
Publication date: 8 October 2014
Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)
Abstract: Many biochemical and industrial applications involve complicated networks of simultaneously occurring chemical reactions. Under the assumption of mass action kinetics, the dynamics of these chemical reaction networks are governed by systems of polynomial ordinary differential equations. The steady states of these mass action systems have been analysed via a variety of techniques, including elementary flux mode analysis, algebraic techniques (e.g. Groebner bases), and deficiency theory. In this paper, we present a novel method for characterizing the steady states of mass action systems. Our method explicitly links a network's capacity to permit a particular class of steady states, called toric steady states, to topological properties of a related network called a translated chemical reaction network. These networks share their reaction stoichiometries with their source network but are permitted to have different complex stoichiometries and different network topologies. We apply the results to examples drawn from the biochemical literature.
Full work available at URL: https://arxiv.org/abs/1305.5845
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Cited In (37)
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