A computational approach to steady state correspondence of regular and generalized mass action systems
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Publication:891844
Abstract: It has been recently observed that the dynamical properties of mass action systems arising from many models of biochemical reaction networks can be derived by considering the corresponding properties of a related generalized mass action system. The correspondence process known as network translation in particular has been shown to be useful in characterizing a system's steady states. In this paper, we further develop the theory of network translation with particular focus on a subclass of translations known as improper translations. For these translations, we derive conditions on the network topology of the translated network which are sufficient to guarantee the original and translated systems share the same steady states. We then present a mixed-integer linear programming (MILP) algorithm capable of determining whether a mass action system can be corresponded to a generalized system through the process of network translation.
Recommendations
- Network translation and steady-state properties of chemical reaction systems
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Cited in
(14)- Network translation and steady-state properties of chemical reaction systems
- A generalization of Birch's theorem and vertex-balanced steady states for generalized mass-action systems
- On the bijectivity of families of exponential/generalized polynomial maps
- Complex Balanced Equilibria of Weakly Reversible Poly-Pl Systems: Existence, Stability, and Robustness
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- Analysis of mass-action systems by split network translation
- A decomposition-based approach for deriving positive steady states of a class of chemical reaction networks with non-mass-action kinetics
- A deficiency-based approach to parametrizing positive equilibria of biochemical reaction systems
- Computing weakly reversible deficiency zero network translations using elementary flux modes
- A linear programming approach to dynamical equivalence, linear conjugacy, and the deficiency one theorem
- Translated chemical reaction networks
- Sufficient Conditions for Linear Stability of Complex-Balanced Equilibria in Generalized Mass-Action Systems
- Computational Translation Framework Identifies Biochemical Reaction Networks with Special Topologies and Their Long-Term Dynamics
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