A viral propagation model with a nonlinear infection rate and free boundaries

DOI10.1007/S11425-020-1680-0MaRDI QIDQ2236588zbMATH OpenOpenAlexFDO

Authors Lei Li, Siyu Liu, Mingxin Wang

Publication date 25 October 2021

Published in Science China. Mathematics (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1912.03597

zbMATH Keywords

basic reproduction numberlong time behaviorfree boundariesspreading-vanishingviral propagation model

Mathematics Subject Classification ID

Epidemiology (92D30) Asymptotic behavior of solutions to PDEs (35B40) Existence problems for PDEs: global existence, local existence, non-existence (35A01) Uniqueness problems for PDEs: global uniqueness, local uniqueness, non-uniqueness (35A02) Reaction-diffusion equations (35K57) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Free boundary problems for PDEs (35R35)

Abstract: In this paper we put forward a viral propagation model with nonlinear infection rate and free boundaries and investigate the dynamical properties. This model is composed of two ordinary differential equations and one partial differential equation, in which the spatial range of the first equation is the whole space $mathbbR$, and the last two equations have free boundaries. As a new mathematical model, we prove the existence, uniqueness and uniform estimates of global solution, and provide the criteria for spreading and vanishing, and long time behavior of the solution components $u,v,w$. Comparing with the corresponding ordinary differential systems, the {it Basic Reproduction Number} ${calR}_0$ plays a different role. We find that when ${calR}_{0}le1$, the virus cannot spread successfully; when ${calR}_0>1$, the successful spread of virus depends on the initial value and varying parameters.

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Cited in

(12)

• A diffusive viral propagation model with nonlinear infection rate and free boundaries
• Free boundary problems for the local-nonlocal diffusive model with different moving parameters
• The dynamics of partially degenerate nonlocal diffusion systems with free boundaries
• Dynamics of a nonlinear infection viral propagation model with one fixed boundary and one free boundary
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