A viral propagation model with a nonlinear infection rate and free boundaries

DOI10.1007/S11425-020-1680-0zbMATH Open1479.35888arXiv1912.03597OpenAlexW3033429502MaRDI QIDQ2236588FDOQ2236588

Mingxin Wang, Lei Li, Siyu Liu

Publication date: 25 October 2021

Published in: Science China. Mathematics (Search for Journal in Brave)

Abstract: In this paper we put forward a viral propagation model with nonlinear infection rate and free boundaries and investigate the dynamical properties. This model is composed of two ordinary differential equations and one partial differential equation, in which the spatial range of the first equation is the whole space $mathbbR$, and the last two equations have free boundaries. As a new mathematical model, we prove the existence, uniqueness and uniform estimates of global solution, and provide the criteria for spreading and vanishing, and long time behavior of the solution components $u,v,w$. Comparing with the corresponding ordinary differential systems, the {it Basic Reproduction Number} ${calR}_0$ plays a different role. We find that when ${calR}_{0}le1$, the virus cannot spread successfully; when ${calR}_0>1$, the successful spread of virus depends on the initial value and varying parameters.

Full work available at URL: https://arxiv.org/abs/1912.03597

zbMATH Keywords

basic reproduction numberlong time behaviorfree boundariesspreading-vanishingviral propagation model

Mathematics Subject Classification ID

Epidemiology (92D30) Asymptotic behavior of solutions to PDEs (35B40) Existence problems for PDEs: global existence, local existence, non-existence (35A01) Uniqueness problems for PDEs: global uniqueness, local uniqueness, non-uniqueness (35A02) Reaction-diffusion equations (35K57) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Free boundary problems for PDEs (35R35)

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Cited In (12)

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