The structure of allelic diversity in the presence of purifying selection

DOI10.1016/j.tpb.2011.12.002zbMath1322.92045arXiv1010.2478OpenAlexW2110123613WikidataQ36901012 ScholiaQ36901012MaRDI QIDQ2261860

Michael M. Desai, Joshua B. Plotkin, Aleksandra M. Walczak, Lauren E. Nicolaisen

Publication date: 13 March 2015

Published in: Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1010.2478

zbMATH Keywords

Ewens sampling formulalinkagepurifying selectionallelic diversity

Mathematics Subject Classification ID

Problems related to evolution (92D15) Genetics and epigenetics (92D10)

Related Items (2)

Statistical questions in experimental evolution ⋮ Speed of evolution in large asexual populations with diminishing returns

Cites Work

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• A coalescent dual process in a Moran model with genic selection
• The accumulation of deleterious genes in a population - Muller's Ratchet
• Allele frequencies with genic selection
• Frequency spectra of neutral and deleterious alleles in a finite population
• Convergence to Fleming-Viot processes in the weak atomic topology
• Mathematical population genetics. I: Theoretical introduction.
• Approximate Ewens formulae for symmetric overdominance selection
• The distribution of rare alleles
• Mutation-selection balance: ancestry, load, and maximum principle
• The sampling theory of selectively neutral alleles
• Addendum to a paper of W. Ewens
• Robustness of the Ewens sampling formula
• A coalescent dual process in a Moran model with genic selection, and the lambda coalescent limit

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