A Markov random field-based approach to characterizing human brain development using spatial-temporal transcriptome data

DOI10.1214/14-AOAS802zbMath1454.62352arXiv1506.00480WikidataQ31045903 ScholiaQ31045903MaRDI QIDQ2349587

Hongyu Zhao, Matthew W. State, Zhixiang Lin, Stephan J. Sanders, Mingfeng Li, Nenad Sestan

Publication date: 17 June 2015

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1506.00480

zbMATH Keywords

differential expressionmicroarraygene expressionMarkov random field modelneurodevelopmentMonte Carlo expectation-maximization algorithmspatial and temporal data

Mathematics Subject Classification ID

Random fields; image analysis (62M40) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Related Items (4)

A Markov random field-based approach for joint estimation of differentially expressed genes in mouse transcriptome data ⋮ On Joint Estimation of Gaussian Graphical Models for Spatial and Temporal Data ⋮ Change-detection-assisted multiple testing for spatiotemporal data ⋮ A Markov random field-based approach to characterizing human brain development using spatial-temporal transcriptome data

Uses Software

• DAVID

Cites Work

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• A hidden spatial-temporal Markov random field model for network-based analysis of time course gene expression data
• Hidden Markov Models for Microarray Time Course Data in Multiple Biological Conditions
• Large-Scale Simultaneous Hypothesis Testing
• Functional Hierarchical Models for Identifying Genes with Different Time‐Course Expression Profiles

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