Loss- and gain-of-function mutations in cancer: mass-action, spatial and hierarchical models
DOI10.1007/S10955-006-9238-0zbMATH Open1115.92029OpenAlexW2027243324MaRDI QIDQ2641406FDOQ2641406
Authors: Natalia L. Komarova
Publication date: 20 August 2007
Published in: Journal of Statistical Physics (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1007/s10955-006-9238-0
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- Mutation-selection networks of cancer initiation: tumor suppressor genes and chromosomal instability
- Epithelial tissue architecture protects against cancer
Cited In (13)
- Spatial stochastic models for cancer initiation and progression
- A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt
- Gain and loss of function mutations in biological chemical reaction networks: a mathematical model with application to colorectal cancer cells
- STOCHASTIC MODELING OF LOSS- AND GAIN-OF-FUNCTION MUTATIONS IN CANCER
- Structure-functional prediction and analysis of cancer mutation effects in protein kinases
- Spatial invasion dynamics on random and unstructured meshes: implications for heterogeneous tumor populations
- A general multi-scale description of metastable adaptive motion across fitness valleys
- Spread of premalignant mutant clones and cancer initiation in multilayered tissue
- Spatial Moran models I. stochastic tunneling in the neutral case
- Somatic selection for and against cancer
- Epithelial tissue architecture protects against cancer
- A stochastic model of cancer initiation including a bystander effect
- A hierarchical probability model of colon cancer
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