Loss- and gain-of-function mutations in cancer: mass-action, spatial and hierarchical models

DOI10.1007/s10955-006-9238-0zbMath1115.92029OpenAlexW2027243324MaRDI QIDQ2641406

Natalia L. Komarova

Publication date: 20 August 2007

Published in: Journal of Statistical Physics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s10955-006-9238-0

zbMATH Keywords

Moran processstem cellsstochastic tunnelingnearest neighbor interactionsoncogenestumor suppressor genesfinite branching processhomeostatic control

Mathematics Subject Classification ID

Applications of branching processes (60J85) Medical applications (general) (92C50) Population dynamics (general) (92D25) Branching processes (Galton-Watson, birth-and-death, etc.) (60J80)

Related Items (4)

A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt ⋮ Spatial invasion dynamics on random and unstructured meshes: implications for heterogeneous tumor populations ⋮ A Hierarchical Probability Model of Colon Cancer ⋮ Spatial Moran models I. stochastic tunneling in the neutral case

Uses Software

• pyuvdata

Cites Work

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