Combinatorics of ancestral lines for a Wright-Fisher diffusion with selection in a Lévy environment

DOI10.1214/23-AAP1936MaRDI QIDQ6138926FDO

Authors Grégoire Véchambre

Publication date 16 January 2024

Published in The Annals of Applied Probability (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/2103.12301

zbMATH Keywords

dualityrandom environmentWright-Fisher diffusionMoran modelancestral selection graph

Mathematics Subject Classification ID

Problems related to evolution (92D15) Continuous-time Markov processes on general state spaces (60J25) Continuous-time Markov processes on discrete state spaces (60J27) Interacting particle systems in time-dependent statistical mechanics (82C22)

Abstract: Wright-Fisher diffusions describe the evolution of the type composition of an infinite haploid population with two types (say type $0$ and type $1$) subject to neutral reproductions, and possibly selection and mutations. In the present paper we study a Wright-Fisher diffusion in a L'evy environment that gives a selective advantage to sometimes one type, sometimes the other. Classical methods using the Ancestral Selection Graph (ASG) fail in the study of this model because of the complexity, resulting from the two-sided selection, of the structure of the information contained in the ASG. We propose a new method that consists in encoding the relevant combinatorics of the ASG into a function. We show that the expectations of the coefficients of this function form a (non-stochastic) semigroup and deduce that they satisfy a linear system of differential equations. As a result we obtain a series representation for the fixation probability $h(x)$ (where $x$ is the initial proportion of individuals of type $0$ in the population) as an infinite sum of polynomials whose coefficients satisfy explicit linear relations. Our approach then allows to derive Taylor expansions at every order for $h(x)$ near $x=0$ and to obtain an explicit recursion formula for the coefficients.

Recommendations

• Looking down in the ancestral selection graph: a probabilistic approach to the common ancestor type distribution
• Moran models and Wright–Fisher diffusions with selection and mutation in a one-sided random environment
• Duality, ancestral and diffusion processes in models with selection
• The common ancestor type distribution of a \(\Lambda\)-Wright-Fisher process with selection and mutation
• Duality and fixation in \(\Xi\)-Wright-Fisher processes with frequency-dependent selection

Cites work

• Ancestral processes with selection
• Coalescent approximation for structured populations in a stationary random environment
• Duality and fixation in \(\Xi\)-Wright-Fisher processes with frequency-dependent selection
• General selection models: Bernstein duality and minimal ancestral structures
• Looking down in the ancestral selection graph: a probabilistic approach to the common ancestor type distribution
• Moran models and Wright–Fisher diffusions with selection and mutation in a one-sided random environment
• On the Simpson index for the Wright-Fisher process with random selection and immigration
• On the notion(s) of duality for Markov processes
• Random temporal variation in selection intensities: Case of large population size
• Random temporal variation in selection intensities: One-locus two-allele model
• Scaling limits of population and evolution processes in random environment
• Temporal fluctuations in selection intensities: Case of small population size
• The effects of stochastic environments on allele frequencies in natural populations
• The fixation time of a strongly beneficial allele in a structured population
• The spatial Lambda-Fleming-Viot process with fluctuating selection

Cited in

(1)

• Moran models and Wright–Fisher diffusions with selection and mutation in a one-sided random environment

This page was built for publication: Combinatorics of ancestral lines for a Wright-Fisher diffusion with selection in a Lévy environment

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q6138926)