Modeling of adaptive immunity uncovers disease tolerance mechanisms

DOI10.1016/J.JTBI.2023.111498zbMATH Open1518.92044MaRDI QIDQ6174232FDOQ6174232

Author name not available (Why is that?)

Publication date: 14 July 2023

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

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zbMATH Keywords

immunologybifurcation analysislimit cyclesregions of attractiondisease tolerance

Mathematics Subject Classification ID

Qualitative investigation and simulation of ordinary differential equation models (34C60) Pathology, pathophysiology (92C32)

Cites Work

• Simulating, Analyzing, and Animating Dynamical Systems
• The dynamics of acute inflammation
• A reduced mathematical model of the acute inflammatory response. I: Derivation of model and analysis of anti-inflammation
• Mathematical modeling of energy consumption in the acute inflammatory response
• Using nonlinear model predictive control to find optimal therapeutic strategies to modulate inflammation
• A data-driven model of the role of energy in sepsis

Cited In (4)

• Modeling immunotherapy for allergy
• A minimal model of T cell avidity may identify subtherapeutic vaccine schedules
• Basic Principles in Modeling Adaptive Regulation and Immunodominance
• The benefits of diversity: heterogenous DC populations allow for both immunity and tolerance

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