Controlling the false-discovery rate by procedures adapted to the length bias of RNA-seq

DOI10.1016/J.JKSS.2017.08.001zbMATH Open1390.62324OpenAlexW2760017307MaRDI QIDQ684055FDOQ684055

Authors: Tae Young Yang, Seongmun Jeong 

Publication date: 9 February 2018

Published in: Journal of the Korean Statistical Society (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jkss.2017.08.001

Recommendations

• Detecting differential expression in RNA-sequence data using quasi-likelihood with shrunken dispersion estimates
• Modifying SAMseq to account for asymmetry in the distribution of effect sizes when identifying differentially expressed genes
• Empirical Bayes analysis of RNA sequencing experiments with auxiliary information
• False discovery rate control with groups
• No counts, no variance: allowing for loss of degrees of freedom when assessing biological variability from RNA-seq data

zbMATH Keywords

length biasRNA-Seqcommon weightindividual weightseparate procedureweighted procedure

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Protein sequences, DNA sequences (92D20)

Cites Work

• Title not available (Why is that?)
• Simultaneous Testing of Grouped Hypotheses: Finding Needles in Multiple Haystacks
• A Direct Approach to False Discovery Rates
• High-dimensional variable selection
• Genome-wide significance levels and weighted hypothesis testing
• False discovery control with p-value weighting
• Simultaneous inference: when should hypothesis testing problems be combined?
• Comment: ``Microarrays, empirical Bayes and the two-groups model

Uses Software

• Bioconductor
• edgeR
• DEGseq
• BaySeq
• DEseq

This page was built for publication: Controlling the false-discovery rate by procedures adapted to the length bias of RNA-seq

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q684055)