A modelling framework for gene regulatory networks including transcription and translation
DOI10.1007/S11538-015-0073-9zbMATH Open1335.92031OpenAlexW1965421273WikidataQ50950039 ScholiaQ50950039MaRDI QIDQ891836FDOQ891836
Authors: R. Edwards, A. Machina, Geoffrey McGregor, P. van den Driessche 
Publication date: 17 November 2015
Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1007/s11538-015-0073-9
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singular perturbationgene regulationpiecewise-linearmRNA-protein modeltranscription-translation model
Biochemistry, molecular biology (92C40) Systems biology, networks (92C42) Discontinuous ordinary differential equations (34A36)
Cites Work
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Cited In (22)
- The hidden sensitivity of non-smooth dynamics
- Integrated Circuit Modeling of Biocellular Post-Transcription Gene Mechanisms Regulated by MicroRNA and Proteasome
- Super-transient scaling in time-delay autonomous Boolean network motifs
- Hidden bifurcations and attractors in nonsmooth dynamical systems
- The Regulation of Gene Expression by Operons and the Local Modeling Framework
- Title not available (Why is that?)
- Autoregulation of transcription and translation: a qualitative analysis
- Bifurcations in the interplay of messenger RNA, protein and nonprotein coding RNA
- Hybrid models of genetic networks: mathematical challenges and biological relevance
- Into higher dimensions for nonsmooth dynamical systems
- Convergence properties of posttranslationally modified protein-protein switching networks with fast decay rates
- Smoothing tautologies, hidden dynamics, and sigmoid asymptotics for piecewise smooth systems
- Global dynamics for steep nonlinearities in two dimensions
- Effect of model selection on prediction of periodic behavior in gene regulatory networks
- Dynamics of complex feedback architectures in metabolic pathways
- Title not available (Why is that?)
- Global dynamics for switching systems and their extensions by linear differential equations
- Optimal switching paths of a non-Markovian model of gene bursty expression
- Dynamics of transcription-translation networks
- Combinatorial representation of parameter space for switching networks
- Analysis of a genetic-metabolic oscillator with piecewise linear models
- Comparison of combinatorial signatures of global network dynamics generated by two classes of ODE models
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