Exact solutions for the selection-mutation equilibrium in the Crow-Kimura evolutionary model

DOI10.1016/J.MBS.2015.05.002zbMATH Open1328.92051arXiv1408.4417OpenAlexW2963562822WikidataQ50909180 ScholiaQ50909180MaRDI QIDQ899069FDOQ899069

Yuri S. Semenov, Artem S. Novozhilov

Publication date: 21 December 2015

Published in: Mathematical Biosciences (Search for Journal in Brave)

Abstract: We reformulate the eigenvalue problem for the selection--mutation equilibrium distribution in the case of a haploid asexually reproduced population in the form of an equation for an unknown probability generating function of this distribution. The special form of this equation in the infinite sequence limit allows us to obtain analytically the steady state distributions for a number of particular cases of the fitness landscape. The general approach is illustrated by examples; theoretical findings are compared with numerical calculations.

Full work available at URL: https://arxiv.org/abs/1408.4417

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zbMATH Keywords

error thresholdCrow-Kimura modelquasispecies modelselection-mutation equilibriumsingle peaked landscape

Mathematics Subject Classification ID

Problems related to evolution (92D15) Eigenvalues, singular values, and eigenvectors (15A18) Population dynamics (general) (92D25)

Cites Work

• Spectral properties of Eigen evolution matrices
• On Eigen's theory of the self-organization of matter and the evolution of biological macromolecules
• Mutation-selection balance: ancestry, load, and maximum principle
• Title not available (Why is that?)
• Title not available (Why is that?)
• On the behavior of the leading eigenvalue of Eigen's evolutionary matrices
• Linear algebra of the permutation invariant Crow-Kimura model of prebiotic evolution
• Mutation, selection, and ancestry in branching models: a variational approach
• A new method for the solution of models of biological evolution: Derivation of exact steady-state distributions
• Title not available (Why is that?)
• Finite genome length corrections for the mean fitness and gene probabilities in evolution models
• What is the difference between models of error thresholds and Muller's ratchet?

Cited In (16)

• Open quasispecies models: stability, optimization, and distributed extension
• Generalized quasispecies model on finite metric spaces: isometry groups and spectral properties of evolutionary matrices
• STATIONARY SOLUTIONS OF A SELECTION MUTATION MODEL: THE PURE MUTATION CASE
• Evolutionary computation and Wright's equation.
• Analytical solution of the evolution dynamics on a multiplicative-fitness landscape
• An Exactly Solved Model for Mutation, Recombination and Selection
• Evolutionary dynamics and eigenspectrum of confluent Heun equation
• On Eigen's quasispecies model, two-valued fitness landscapes, and isometry groups acting on finite metric spaces
• Equilibrium state of molecular breeding
• Quasispecies on class-dependent fitness landscapes
• Stationary mutant distributions and evolutionary optimization
• The dynamical way to mutation-selection balance of an infinite population evolving on a truncated fitness landscape
• Cumulant dynamics of a population under multiplicative selection, mutation, and drift.
• Numerical and exact solutions for continuum of alleles models
• On the behavior of the leading eigenvalue of Eigen's evolutionary matrices
• A new method for the solution of models of biological evolution: Derivation of exact steady-state distributions

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