Adaptive Bayesian compound designs for dose finding studies

DOI10.1016/J.JSPI.2011.12.029MaRDI QIDQ434557zbMATH OpenOpenAlexWikidataFDO

Authors J. A. Eccleston, T. Goggin, J. M. McGree, C. C. Drovandi, M. H. Thompson, S. B. Duffull, K. Mengersen, A. N. Pettitt

Publication date 16 July 2012

Published in Journal of Statistical Planning and Inference (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jspi.2011.12.029

zbMATH Keywords

adaptive designcompound utilityimportance samplingMarkov chain Monte Carlooptimal designsafetyutility functions

Mathematics Subject Classification ID

Bayesian inference (62F15) Applications of statistics to biology and medical sciences; meta analysis (62P10) Probabilistic models, generic numerical methods in probability and statistics (65C20) Numerical analysis or methods applied to Markov chains (65C40)

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Cites work

• A Method for Obtaining and Analyzing Sensitivity Data
• A Stochastic Approximation Method
• Adaptive designs for selecting drug combinations based on efficacy-toxicity response
• Bayesian decision procedures based on logistic regression models for dose-finding studies
• Bayesian optimal designs for phase I clinical trials
• Compound optimal designs for percentile estimation in dose-response models with restricted design intervals
• Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
• Easy-to-implement Bayesian methods for dose-escalation studies in healthy volunteers
• scientific article; zbMATH DE number 47310 (Why is no real title available?)
• Implementation of a Bayesian Design in a Dose‐Escalation Study of an Experimental Agent in Healthy Volunteers
• Markov chains for exploring posterior distributions. (With discussion)
• Miscellanea. A stopping rule for the continual reassessment method
• Nonlinear Experiments: Optimal Design and Inference Based on Likelihood
• Optimal Bayesian-feasible dose escalation for cancer phase I trials
• Patient‐Specific Dose Finding Based on Bivariate Outcomes and Covariates
• Selection of Dose Levels for Estimating a Percentage Point of a Logistic Quantal Response Curve
• Sequential Experimental Designs for Generalized Linear Models
• Simulation-based sequential Bayesian design
• Statistical Methods for Dose‐Finding Experiments

Cited in

(18)

• Evaluation of the Fisher information matrix in nonlinear mixed effect models using adaptive Gaussian quadrature
• Developments of the total entropy utility function for the dual purpose of model discrimination and parameter estimation in Bayesian design
• Bayesian sequential design for copula models
• A Laplace-based algorithm for Bayesian adaptive design
• Sequential Monte Carlo for Bayesian sequentially designed experiments for discrete data
• Adaptive clinical trial designs for phase I cancer studies
• Bayesian dose finding for combined drugs with discrete and continuous doses
• scientific article; zbMATH DE number 5898591 (Why is no real title available?)
• Adaptive Dc-optimal designs for dose finding based on a continuous efficacy endpoint
• A pseudo-marginal sequential Monte Carlo algorithm for random effects models in Bayesian sequential design
• scientific article; zbMATH DE number 1984442 (Why is no real title available?)
• A combined proof of concept and dose finding study with multiple endpoints: A Bayesian adaptive design in chronic prostatitis/chronic pelvic pain syndrome
• Implementation of a Bayesian Design in a Dose‐Escalation Study of an Experimental Agent in Healthy Volunteers
• A Review of Modern Computational Algorithms for Bayesian Optimal Design
• Adaptive Bayesian phase I clinical trial designs for estimating the maximum tolerated doses for two drugs while fully utilizing all toxicity information
• Response-adaptive randomization in clinical trials: from myths to practical considerations
• Bayesian adaptive \(N\)-of-1 trials for estimating population and individual treatment effects
• A Bayesian dose-finding design for drug combination trials with delayed toxicities

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