Crossing a fitness valley as a metastable transition in a stochastic population model
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Publication:2299586
Abstract: We consider a stochastic model of population dynamics where each individual is characterised by a trait in {0,1,...,L} and has a natural reproduction rate, a logistic death rate due to age or competition and a probability of mutation towards neighbouring traits at each reproduction event. We choose parameters such that the induced fitness landscape exhibits a valley: mutant individuals with negative fitness have to be created in order for the population to reach a trait with positive fitness. We focus on the limit of large population and rare mutations at several speeds. In particular, when the mutation rate is low enough, metastability occurs: the exit time of the valley is random, exponentially distributed.
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Cites work
- scientific article; zbMATH DE number 3951715 (Why is no real title available?)
- A microscopic interpretation for adaptive dynamics trait substitution sequence models
- A microscopic probabilistic description of a locally regulated population and macroscopic approximations
- A stochastic model for speciation by mating preferences
- Adaptive dynamics, a geometrical study of the consequences of nearly faithful reproduction
- Conditional distributions and waiting times in multitype branching processes
- Convergence of an infinite dimensional stochastic process to a spatially structured trait substitution sequence
- Dynamics of escape mutants
- Evolutionary dynamics of invasion and escape
- From Individual Stochastic Processes to Macroscopic Models in Adaptive Evolution
- From stochastic, individual-based models to the canonical equation of adaptive dynamics in one step
- Genealogies of two linked neutral loci after a selective sweep in a large population of stochastically varying size
- Large population limit and time behaviour of a stochastic particle model describing an age-structured population
- Metastability. A potential-theoretic approach
- Multitype Bienaymé–Galton–Watson processes escaping extinction
- On the Waiting Time to Escape
- On time scales and quasi-stationary distributions for multitype birth-and-death processes
- Polymorphic evolution sequence and evolutionary branching
- Random graphs and complex networks. Volume 1
- Sharp asymptotics for the quasi-stationary distribution of birth-and-death processes
- Stochastic epidemics in a homogeneous community
- The dynamical theory of coevolution: A derivation from stochastic ecological processes
- The effect of recurrent mutations on genetic diversity in a large population of varying size
- The interplay of two mutations in a population of varying size: A stochastic eco-evolutionary model for clonal interference
- The pace of evolution across fitness valleys
- The rate at which asexual populations cross fitness valleys
- The recovery of a recessive allele in a Mendelian diploid model
- Trait substitution trees on two time scales analysis
- Traveling waves of selective sweeps
- Using moment equations to understand stochastically driven spatial pattern formation in ecological systems
Cited in
(16)- Population dynamics and statistical physics in synergy. Abstracts from the workshop held March 6--12, 2022
- The calculation of mean first arrival time for double mutants, crossing the fitness valley
- Filling the gap between individual-based evolutionary models and Hamilton-Jacobi equations
- scientific article; zbMATH DE number 7662455 (Why is no real title available?)
- The rate at which asexual populations cross fitness valleys
- A general multi-scale description of metastable adaptive motion across fitness valleys
- On \(\Lambda\)-Fleming-Viot processes with general frequency-dependent selection
- Fitness-valley crossing with generalized parent-offspring transmission
- Metastable evolutionary dynamics: crossing fitness barriers or escaping via neutral paths?
- Multiscale eco-evolutionary models: from individuals to populations
- Stochastic analysis of emergence of evolutionary cyclic behavior in population dynamics with transfer
- From adaptive dynamics to adaptive walks
- Sharp approximation and hitting times for stochastic invasion processes
- Stochastic individual-based models with power law mutation rate on a general finite trait space
- The pace of evolution across fitness valleys
- Crossing time through the fitness barrier in an asymmetric multiplicative or additive landscape in the mutation-selection model
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