What if we ignore the random effects when analyzing RNA-seq data in a multifactor experiment

DOI10.1515/SAGMB-2015-0011zbMath1343.92009OpenAlexW2320596164WikidataQ31050282 ScholiaQ31050282MaRDI QIDQ306675

Shiqi Cui, Jilong Li, Jianlin Cheng, Jing Qiu, Tieming Ji

Publication date: 1 September 2016

Published in: Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1515/sagmb-2015-0011

zbMATH Keywords

random effectsgeneralized linear mixed modelsmethod comparisonmultifactor experimentsRNA-seq data analysis

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) General biostatistics (92B15) Generalized linear models (logistic models) (62J12) Genetics and epigenetics (92D10)

Related Items (2)

A Bayesian model to identify multiple expression patterns with simultaneous FDR control for a multi-factor RNA-seq experiment ⋮ Poisson–Tweedie mixed-effects model: A flexible approach for the analysis of longitudinal RNA-seq data

Uses Software

• DEseq
• QuasiSeq
• ShrinkBayes
• EBSeq

Cites Work

• Unnamed Item
• Unnamed Item
• Detecting Differential Expression in RNA-sequence Data Using Quasi-likelihood with Shrunken Dispersion Estimates
• A two-stage Poisson model for testing RNA-Seq data
• A Direct Approach to False Discovery Rates
• Negative binomial loglinear mixed models

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