Accuracy of multiscale reduction for stochastic reaction systems
From MaRDI portal
Publication:5022754
Abstract: Stochastic models of chemical reaction networks are an important tool to describe and analyze noise effects in cell biology. When chemical species and reaction rates in a reaction system have different orders of magnitude, the associated stochastic system is often modeled in a multiscale regime. It is known that multiscale models can be approximated with a reduced system such as mean field dynamics or hybrid systems, but the accuracy of the approximation remains unknown. In this paper, we estimate the probability distribution of low copy species in multiscale stochastic reaction systems under short-time scale. We also establish an error bound for this approximation. Throughout the manuscript, typical mass action systems are mainly handled, but we also show that the main theorem can extended to general kinetics, which generalizes existing results in the literature. Our approach is based on a direct analysis of the Kolmogorov equation, in contrast to classical approaches in the existing literature.
Recommendations
- A reduction method for multiple time scale stochastic reaction networks
- Reduction for stochastic biochemical reaction networks with multiscale conservations
- Error analysis of diffusion approximation methods for multiscale systems in reaction kinetics
- Asymptotic analysis of multiscale approximations to reaction networks
- Error bound for hybrid models of two-scaled stochastic reaction systems
Cites work
- scientific article; zbMATH DE number 3400258 (Why is no real title available?)
- Accurate chemical master equation solution using multi-finite buffers
- Asymptotic analysis of multiscale approximations to reaction networks
- Embracing noise in chemical reaction networks
- Finite Time Distributions of Stochastically Modeled Chemical Systems with Absolute Concentration Robustness
- Linear Generalizations of Gronwall's Inequality
- Markov Chains
- Product-form stationary distributions for deficiency zero chemical reaction networks
- Quasi-steady-state approximations derived from the stochastic model of enzyme kinetics
- Reduction for stochastic biochemical reaction networks with multiscale conservations
- Scaling limits of spatial compartment models for chemical reaction networks
- Separation of time-scales and model reduction for stochastic reaction networks
- Solving the chemical master equation for monomolecular reaction systems analytically
- Stability of Markovian processes III: Foster–Lyapunov criteria for continuous-time processes
- The Finite State Projection Approach for the Analysis of Stochastic Noise in Gene Networks
Cited in
(16)- Revisiting moment-closure methods with heterogeneous multiscale population models
- Stochastic approximations of higher-molecular by bi-molecular reactions
- Separation of time-scales and model reduction for stochastic reaction networks
- Asymptotic analysis of multiscale approximations to reaction networks
- Accuracy limitations and the measurement of errors in the stochastic simulation of chemically reacting systems
- Analysis of the Multiplane Method for Stochastic Simulations of Reaction Networks with Fluctuations
- Elimination of intermediate species in multiscale stochastic reaction networks
- Reduction for stochastic biochemical reaction networks with multiscale conservations
- Sensitivity analysis for multiscale stochastic reaction networks using hybrid approximations
- Error analysis of diffusion approximation methods for multiscale systems in reaction kinetics
- Convergence of Regularized Particle Filters for Stochastic Reaction Networks
- Error bound for hybrid models of two-scaled stochastic reaction systems
- Quasi product form approximation for Markov models of reaction networks
- Accuracy analysis of hybrid stochastic simulation algorithm on linear chain reaction systems
- Error bound for piecewise deterministic processes modeling stochastic reaction systems
- Computational Translation Framework Identifies Biochemical Reaction Networks with Special Topologies and Their Long-Term Dynamics
This page was built for publication: Accuracy of multiscale reduction for stochastic reaction systems
Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q5022754)
