A statistical method for detecting differentially expressed SNVs based on next-generation RNA-seq data

DOI10.1111/BIOM.12548zbMATH Open1366.62215OpenAlexW2414674452WikidataQ36045208 ScholiaQ36045208MaRDI QIDQ5347401FDOQ5347401

Authors:

Publication date: 23 May 2017

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc5151178

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zbMATH Keywords

differential expressionRNA-seqlikelihood ratio teststatistical methodallele-specific expressionbreast cancer tumors

Mathematics Subject Classification ID

Parametric hypothesis testing (62F03) Applications of statistics to biology and medical sciences; meta analysis (62P10) Protein sequences, DNA sequences (92D20)

Cites Work

• Title not available (Why is that?)
• A penalized EM algorithm incorporating missing data mechanism for Gaussian parameter estimation

Cited In (4)

• Single-sample SNP detection by empirical Bayes method using next-generation sequencing data
• Analysis of expression profile and gene variation via development of methods for next generation sequencing data
• abSNP: RNA-Seq SNP calling in repetitive regions via abundance estimation
• Zero-Inflated Poisson Models with Measurement Error in the Response

Uses Software

• STAR
• DEseq
• GATK

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