The importance of distinct modeling strategies for gene and gene-specific treatment effects in hierarchical models for microarray data

DOI10.1214/12-AOAS535zbMath1454.62357arXiv1209.6493MaRDI QIDQ714369

Dan Nettleton, Steven P. Lund

Publication date: 21 October 2012

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1209.6493

zbMATH Keywords

uncertainty; EM algorithm; differential expression; random effects; hierarchical models

Mathematics Subject Classification ID

62P10: Applications of statistics to biology and medical sciences; meta analysis

Related Items

The importance of distinct modeling strategies for gene and gene-specific treatment effects in hierarchical models for microarray data, Hierarchical modeling and differential expression analysis for RNA-seq experiments with inbred and hybrid genotypes

Uses Software

• gaga
• EBarrays

Cites Work

• Unnamed Item
• The importance of distinct modeling strategies for gene and gene-specific treatment effects in hierarchical models for microarray data
• Gaga: a parsimonious and flexible model for differential expression analysis
• Bayesian testing of many hypotheses \(\times \) many genes: a study of sleep apnea
• Flexible temporal expression profile modelling using the Gaussian process
• A statistical analysis of memory CD8 T cell differentiation: An application of a hierarchical state space model to a short time course microarray experiment
• A hidden spatial-temporal Markov random field model for network-based analysis of time course gene expression data
• Hidden Markov Models for Microarray Time Course Data in Multiple Biological Conditions
• Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments
• A Unified Approach for Simultaneous Gene Clustering and Differential Expression Identification
• Improved statistical tests for differential gene expression by shrinking variance components estimates
• Mixture Modeling for Genome‐Wide Localization of Transcription Factors
• Exploration, normalization, and summaries of high density oligonucleotide array probe level data
• Detecting differential gene expression with a semiparametric hierarchical mixture method