On the retention of gene duplicates prone to dominant deleterious mutations

DOI10.1016/J.TPB.2014.01.004zbMATH Open1296.92160OpenAlexW2051520313WikidataQ34404465 ScholiaQ34404465MaRDI QIDQ743527FDOQ743527

Authors: Giulia Malaguti, Param Priya Singh, Hervé Isambert 

Publication date: 24 September 2014

Published in: Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL: https://zenodo.org/record/895351

Recommendations

• A diffusion model for the fate of tandem gene duplicates in diploids
• Role of selection in fixation of gene duplications
• Models for loosely linked gene duplicates suggest lengthy persistence of both copies
• Degenerate diffusions arising from gene duplication models
• A diffusion approach to approximating preservation probabilities for gene duplicates

zbMATH Keywords

purifying selectiondominant deleterious mutationspopulation genetics modelssmall scale duplicationwhole-genome duplication

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Population dynamics (general) (92D25)

Cites Work

• Title not available (Why is that?)
• Title not available (Why is that?)
• Title not available (Why is that?)
• The allele-frequency spectrum in a decoupled Moran model with mutation, drift, and directional selection, assuming small mutation rates
• A coalescent dual process in a Moran model with genic selection
• A coalescent dual process in a Moran model with genic selection, and the lambda coalescent limit
• Role of selection in fixation of gene duplications
• Title not available (Why is that?)

Cited In (1)

• Role of selection in fixation of gene duplications

Uses Software

• PSI-BLAST
• BLAST
• UniProt
• GeneCards

This page was built for publication: On the retention of gene duplicates prone to dominant deleterious mutations

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q743527)