Population genetics of tumor suppressor genes

DOI10.1016/J.JTBI.2004.09.001zbMATH Open1442.92103OpenAlexW1997606150WikidataQ57065420 ScholiaQ57065420MaRDI QIDQ781173FDOQ781173

Authors: Yoh Iwasa, Franziska Michor, Natalia L. Komarova, Martin A. Nowak 

Publication date: 16 July 2020

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2004.09.001

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zbMATH Keywords

tumor suppressor genestochastic tunnelingmulti-state branching processsomatic evolution of cancer

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Pathology, pathophysiology (92C32)

Cites Work

• Continuous and discrete mathematical models of tumor-induced angiogenesis
• Title not available (Why is that?)
• Mutation-selection networks of cancer initiation: tumor suppressor genes and chromosomal instability
• MATHEMATICAL MODELLING OF MACROPHAGE DYNAMICS IN TUMOURS

Cited In (20)

• Mutation-selection networks of cancer initiation: tumor suppressor genes and chromosomal instability
• Forward and backward evolutionary processes and allele frequency spectrum in a cancer cell population
• On mutations in the branching model for multitype populations
• Stochastic modeling of stem-cell dynamics with control
• Multifocality and recurrence risk: a quantitative model of field cancerization
• Stochastic tunneling in the colonization of mutualistic organisms: primary succession by mycorrhizal plants
• Cancer initiation with epistatic interactions between driver and passenger mutations
• Evolutionary dynamics of tumor progression with random fitness values
• Dynamics of metastasis suppressor gene inactivation
• Genetic instability and clonal expansion
• Exact solution of a two-type branching process: clone size distribution in cell division kinetics
• A mathematical model of breast cancer development, local treatment and recurrence
• The waiting time for a second mutation: an alternative to the Moran model
• A spatial mutation model with increasing mutation rates
• Bisexual branching processes to model extinction conditions for Y-linked genes
• Evolutionary dynamics of BRCA1 alterations in breast tumorigenesis
• Evolution of resistance and progression to disease during clonal expansion of cancer
• The rate of multi-step evolution in Moran and Wright-Fisher populations
• Mutation timing in a spatial model of evolution
• Computational modeling of early-stage breast cancer progression using TPFA method: a numerical investigation

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