Population genetics of tumor suppressor genes

DOI10.1016/J.JTBI.2004.09.001MaRDI QIDQ781173zbMATH OpenOpenAlexWikidataFDO

Authors Yoh Iwasa, Franziska Michor, Natalia L. Komarova, Martin A. Nowak

Publication date 16 July 2020

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2004.09.001

zbMATH Keywords

tumor suppressor genestochastic tunnelingmulti-state branching processsomatic evolution of cancer

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Pathology, pathophysiology (92C32)

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Cites work

• scientific article; zbMATH DE number 3194920 (Why is no real title available?)
• Continuous and discrete mathematical models of tumor-induced angiogenesis
• MATHEMATICAL MODELLING OF MACROPHAGE DYNAMICS IN TUMOURS
• Mutation-selection networks of cancer initiation: tumor suppressor genes and chromosomal instability

Cited in

(20)

• Genetic instability and clonal expansion
• Stochastic modeling of stem-cell dynamics with control
• Cancer initiation with epistatic interactions between driver and passenger mutations
• Mutation timing in a spatial model of evolution
• Evolutionary dynamics of tumor progression with random fitness values
• Stochastic tunneling in the colonization of mutualistic organisms: primary succession by mycorrhizal plants
• Exact solution of a two-type branching process: clone size distribution in cell division kinetics
• Computational modeling of early-stage breast cancer progression using TPFA method: a numerical investigation
• On mutations in the branching model for multitype populations
• Mutation-selection networks of cancer initiation: tumor suppressor genes and chromosomal instability
• Multifocality and recurrence risk: a quantitative model of field cancerization
• Evolution of resistance and progression to disease during clonal expansion of cancer
• Forward and backward evolutionary processes and allele frequency spectrum in a cancer cell population
• Dynamics of metastasis suppressor gene inactivation
• The rate of multi-step evolution in Moran and Wright-Fisher populations
• A mathematical model of breast cancer development, local treatment and recurrence
• Bisexual branching processes to model extinction conditions for Y-linked genes
• The waiting time for a second mutation: an alternative to the Moran model
• Evolutionary dynamics of BRCA1 alterations in breast tumorigenesis
• A spatial mutation model with increasing mutation rates

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