Optimal combined radio- and anti-angiogenic cancer therapy

DOI10.1007/S10957-018-1426-YzbMath1409.49036OpenAlexW2898852451WikidataQ129024291 ScholiaQ129024291MaRDI QIDQ1730431

Heinz Schättler, Helmut Maurer, Urszula Łedzewicz-Kowalewska

Publication date: 6 March 2019

Published in: Journal of Optimization Theory and Applications (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s10957-018-1426-y

zbMATH Keywords

optimal controlnumerical methodsradiotherapycombination therapyanti-angiogenic treatmentsarc parameterization

Mathematics Subject Classification ID

Medical applications (general) (92C50) Optimality conditions for problems involving ordinary differential equations (49K15) Variational principles of physics (49S05)

Related Items (7)

Measure Optimal Controls for Models Inspired by Biology ⋮ Optimal control for a bone metastasis with radiotherapy model using a linear objective functional ⋮ Combination of antiangiogenic treatment with chemotherapy as a multi‐input optimal control problem ⋮ On the role of the objective in the optimization of compartmental models for biomedical therapies ⋮ Optimal control in reducing side effects during and after chemotherapy of solid tumors ⋮ Optimal control for a mathematical model for chemotherapy with pharmacometrics ⋮ Optimization of antitumor radiotherapy fractionation via mathematical modeling with account of 4 R's of radiobiology

Uses Software

• AMPL
• Ipopt

Cites Work

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