Combination of direct methods and homotopy in numerical optimal control: application to the optimization of chemotherapy in cancer

DOI10.1007/S10957-018-01461-ZzbMath1416.49024arXiv1707.08038OpenAlexW2738623468WikidataQ128719126 ScholiaQ128719126MaRDI QIDQ2420794

Camille Pouchol, Antoine Olivier

Publication date: 7 June 2019

Published in: Journal of Optimization Theory and Applications (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1707.08038

zbMATH Keywords

optimal controlPontryagin's maximum principlehomotopydirect methodsmathematical oncology

Mathematics Subject Classification ID

Numerical methods based on necessary conditions (49M05) Medical applications (general) (92C50) Discrete approximations in optimal control (49M25) Variational principles of physics (49S05)

Related Items (6)

An optimization technique for solving a class of nonlinear fractional optimal control problems: application in cancer treatment ⋮ Generalized Bernoulli polynomials: solving nonlinear 2D fractional optimal control problems ⋮ Asymptotic analysis of selection-mutation models in the presence of multiple fitness peaks ⋮ Evolution of cancer cell populations under cytotoxic therapy and treatment optimisation: insight from a phenotype-structured model ⋮ Discrete and continuum phenotype-structured models for the evolution of cancer cell populations under chemotherapy ⋮ Discrete and Continuum Models for the Evolutionary and Spatial Dynamics of Cancer: A Very Short Introduction Through Two Case Studies

Uses Software

• Ipopt

Cites Work

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