Embeddability of Kimura 3ST Markov matrices
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Publication:1649397
DOI10.1016/J.JTBI.2018.02.005zbMATH Open1397.92466arXiv1703.02263OpenAlexW2963096796WikidataQ49808384 ScholiaQ49808384MaRDI QIDQ1649397FDOQ1649397
Authors: Jordi Roca-Lacostena, Jesús Fernández-Sánchez 
Publication date: 6 July 2018
Published in: Journal of Theoretical Biology (Search for Journal in Brave)
Abstract: In this note, we characterize the embeddability of generic Kimura 3ST Markov matrices in terms of their eigenvalues. As a consequence, we are able to compute the volume of such matrices relative to the volume of all Markov matrices within the model. We also provide examples showing that, in general, mutation rates are not identifiable from substitution probabilities. These examples also illustrate that symmetries between mutation probabilities do not necessarily arise from symmetries between the corresponding mutation rates.
Full work available at URL: https://arxiv.org/abs/1703.02263
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Cited In (8)
- Embeddability and rate identifiability of Kimura 2-parameter matrices
- Maximum likelihood estimation of symmetric group-based models via numerical algebraic geometry
- Embedding of Markov matrices for \(d \leqslant 4\)
- The model-specific Markov embedding problem for symmetric group-based models
- An open set of 4×4 embeddable matrices whose principal logarithm is not a Markov generator
- Notes on Markov embedding
- Embeddability of centrosymmetric matrices capturing the double-helix structure in natural and synthetic DNA
- The embedding problem for Markov matrices
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