n-consistent parameter estimation for systems of ordinary differential equations: bypassing numerical integration via smoothing
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Publication:442091
DOI10.3150/11-BEJ362zbMATH Open1257.49033arXiv1007.3880MaRDI QIDQ442091FDOQ442091
Chris A. J. Klaassen, Shota Gugushvili
Publication date: 9 August 2012
Published in: Bernoulli (Search for Journal in Brave)
Abstract: We consider the problem of parameter estimation for a system of ordinary differential equations from noisy observations on a solution of the system. In case the system is nonlinear, as it typically is in practical applications, an analytic solution to it usually does not exist. Consequently, straightforward estimation methods like the ordinary least squares method depend on repetitive use of numerical integration in order to determine the solution of the system for each of the parameter values considered, and to find subsequently the parameter estimate that minimises the objective function. This induces a huge computational load to such estimation methods. We study the consistency of an alternative estimator that is defined as a minimiser of an appropriate distance between a nonparametrically estimated derivative of the solution and the right-hand side of the system applied to a nonparametrically estimated solution. This smooth and match estimator (SME) bypasses numerical integration altogether and reduces the amount of computational time drastically compared to ordinary least squares. Moreover, we show that under suitable regularity conditions this smooth and match estimation procedure leads to a -consistent estimator of the parameter of interest.
Full work available at URL: https://arxiv.org/abs/1007.3880
Nonparametric regression and quantile regression (62G08) Nonlinear ordinary differential equations and systems (34A34) Numerical methods in optimal control (49M99)
Cites Work
- On the implementation of an interior-point filter line-search algorithm for large-scale nonlinear programming
- Title not available (Why is that?)
- Title not available (Why is that?)
- Weak convergence and empirical processes. With applications to statistics
- Asymptotic Statistics
- Robust Statistics
- Title not available (Why is that?)
- Title not available (Why is that?)
- Title not available (Why is that?)
- Probability Inequalities for Sums of Bounded Random Variables
- Parameter Estimation for Differential Equation Models Using a Framework of Measurement Error in Regression Models
- Asymptotic Properties of Non-Linear Least Squares Estimators
- All of Nonparametric Statistics
- Introduction to nonparametric estimation
- Sieve estimation of constant and time-varying coefficients in nonlinear ordinary differential equation models by considering both numerical error and measurement error
- Title not available (Why is that?)
- A Brief Survey of Bandwidth Selection for Density Estimation
- An Algorithm for Least-Squares Estimation of Nonlinear Parameters
- Optimal plug-in estimators for nonparametric functional estimation
- Nonparametric estimators which can be ``plugged-in.
- Parameter estimation of ODE's via nonparametric estimators
- Recent developments in parameter estimation and structure identification of biochemical and genomic systems
- The use of splines with unknown end points in the identification of systems
- A Spline Least Squares Method for Numerical Parameter Estimation in Differential Equations
- Title not available (Why is that?)
- Asymptotic efficiency and finite-sample properties of the generalized profiling estimation of parameters in ordinary differential equations
- Bandwidth selection: Classical or plug-in?
- Title not available (Why is that?)
- Nonlinear least-squares estimation
- Asymptotic theory of nonlinear least squares estimation
- Nonparametric regression with infinite order flat-top kernels
- Structure and stability of certain chemical networks and applications to the kinetic proofreading model of T-cell receptor signal transduction
- Title not available (Why is that?)
- Estimating a regression function
- Physiological Pharmacokinetic Analysis Using Population Modeling and Informative Prior Distributions
- Gauss and the invention of least squares
- On variance estimation in nonparametric regression
- On Gibb's phase rule
- Contributions to the theory of nonparametric regression, with application to system identification
- Consistency for the least squares estimator in nonparametric regression
- Parameter estimation in dynamic systems
- A new class of kernels for nonparametric curve estimation
- Forcing Function Diagnostics for Nonlinear Dynamics
- Title not available (Why is that?)
- Title not available (Why is that?)
- Bayesian inference for differential equations
Cited In (30)
- Tracking for parameter and state estimation in possibly misspecified partially observed linear ordinary differential equations
- Kernel-Based Profile Estimation for Ordinary Differential Equations with Partially Measured State Variables
- Biochemical systems theory: a review
- Bayesian smooth‐and‐match inference for ordinary differential equations models linear in the parameters
- Differential equations in data analysis
- Characterizability of metabolic pathway systems from time series data
- Consistent estimation of ordinary differential equation when the transformation parameter is unknown
- Robust estimation of parameters in nonlinear ordinary differential equation models
- Two-step Bayesian methods for generalized regression driven by partial differential equations
- Application of one‐step method to parameter estimation in ODE models
- Bayesian analysis of mixed-effect regression models driven by ordinary differential equations
- A model-based initial guess for estimating parameters in systems of ordinary differential equations
- Parameter estimation and forecasting with quantified uncertainty for ordinary differential equation models using \textit{QuantDiffForecast}: a MATLAB toolbox and tutorial
- Data-driven learning of differential equations: combining data and model uncertainty
- Parameter estimation for semiparametric ordinary differential equation models
- Optimal Control and Additive Perturbations Help in Estimating Ill-Posed and Uncertain Dynamical Systems
- Statistical inference for dynamical systems: a review
- Optimal rate of direct estimators in systems of ordinary differential equations linear in functions of the parameters
- Detection of influential measurement for ordinary differential equation with application to HIV dynamics
- A tracking approach to parameter estimation in linear ordinary differential equations
- Separable nonlinear least-squares parameter estimation for complex dynamic systems
- Bayesian two-step estimation in differential equation models
- Numerical discretization-based kernel type estimation methods for ordinary differential equation models
- Consistency of direct integral estimator for partially observed systems of ordinary differential equations
- Parametric Estimation of Ordinary Differential Equations With Orthogonality Conditions
- Modelling motion energy in psychotherapy: a dynamical systems approach
- Generalized Tikhonov regularization in estimation of ordinary differential equations models
- Estimating Varying Coefficients for Partial Differential Equation Models
- Time-course window estimator for ordinary differential equations linear in the parameters
- A regularization method for the parameter estimation problem in ordinary differential equations via discrete optimal control theory
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